Registration Dossier

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Link to relevant study records
Reference
Endpoint:
skin sensitisation
Type of information:
(Q)SAR
Adequacy of study:
disregarded due to major methodological deficiencies
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: The study results are disregarded as the substance is out of the the Applicability Domain (AD) of the model.
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6
Guideline:
other: REACH guidance on QSARs R6, May 2008
Principles of method if other than guideline:
General model for estimating the skin sensitisation.
Details on test animals and environmental conditions:
SMILE:OC(=O)C1CCCCC1
InChI=1/C7H12O2/c8-7(9)6-4-2-1-3-5-6/h6H,1-5H2,(H,8,9)
Interpretation of results:
sensitising
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
The prediction indicates that the substance is sensitizer.The obtained results are disregarded as the substance is out from the applicability domain of the model.
Endpoint conclusion
Endpoint conclusion:
no study available
Additional information:

The study results are disregarded as the substance is out of the the Applicability Domain (AD) of the models. Therefore, no reliable data are available


Migrated from Short description of key information:
No reliable data are available.

Justification for selection of skin sensitisation endpoint:
The study results are disregarded as the substance is out of the the Applicability Domain (AD) of the model.

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no study available

Justification for classification or non-classification