Registration Dossier
Registration Dossier
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EC number: 202-711-3 | CAS number: 98-89-5
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Study period:
- 1986
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- The data obtained from a source of secondary literature are related to a substance which shows the same functional groups . The data derived from read-across is considered reliable because the molecules have the same functional groups due to the action irritating.
Data source
Referenceopen allclose all
- Reference Type:
- secondary source
- Title:
- 3-Cyclohexene-1-carboxylic acid
- Year:
- 2 013
- Bibliographic source:
- CHEMIDplus
- Reference Type:
- secondary source
- Title:
- 3-Cyclohexene-1-carboxylic acid
- Year:
- 2 013
- Bibliographic source:
- RTECS
- Reference Type:
- publication
- Title:
- No information
- Year:
- 1 986
- Bibliographic source:
- Prehled Prumyslove Toxikologie; Organicke Latky,' Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 (-,315,1986)
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- no data
- GLP compliance:
- no
Test material
- Reference substance name:
- 3-Cyclohexene-1-carboxylic acid
- IUPAC Name:
- 3-Cyclohexene-1-carboxylic acid
- Reference substance name:
- Cyclohex-3-ene-1-carboxylic acid
- EC Number:
- 225-314-7
- EC Name:
- Cyclohex-3-ene-1-carboxylic acid
- Cas Number:
- 4771-80-6
- Molecular formula:
- C7H10O2
- IUPAC Name:
- cyclohex-3-ene-1-carboxylic acid
- Test material form:
- not specified
Constituent 1
Constituent 2
Test animals
- Species:
- rabbit
- Strain:
- not specified
Test system
- Type of coverage:
- not specified
- Controls:
- not specified
Results and discussion
In vivo
Results
- Irritation parameter:
- other: REACTION: Severe
- Irritant / corrosive response data:
- REACTION: Severe
Applicant's summary and conclusion
- Interpretation of results:
- irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- According to Directive 67/548/EEC and to Regulation (EC) n. 1272/2008, the substance is classified for this property.
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