Tributyl borate

Water solubility

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

water solubility

Type of information:

other: experimental study on hydrolysis product Boric acid

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Deviations:

not specified

GLP compliance:

yes

Type of method:

flask method

Water solubility:

49.2 g/L

Temp.:

20 °C

pH:

3.7

Details on results:

Preliminary solubility test
The estimated water solubility is approximately 8.29 g/L. This value means that the shake-flask method had to be applied. Because of the theoretical water solubility (47 g/L) the water solubility test was performed using the theoretical value.
The mean value of the water solubility of Test 1, 2 and 3 is 49.20 ± 0.35 g/L.

Solubility (shake flask method): Test number, stirring time, Tyndall value and the water solubility of the test substance at 20 ºC:

Test number	Stirring time (h)	pH	Tyndall	Water solubility (g/L)
1	24	3.75	0.0020 (0.0018)	48.86
2	48	3.54	0.0031 (0.0020)	49.57
3	72	3.98	0.0022 (0.0021)	49.16

The value between parentheses is Tyndall value of the blank.

Conclusions:

The water solubility of the test substance was 49.20 ± 0.35 g/L at 20.0 ± 0.5 ºC.

Interpretation of results: very soluble (> 10000 mg/L).

Reference 2

Endpoint:

water solubility

Type of information:

other: experimental study on hydrolysis product n-Butanol

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Qualifier:

according to guideline

Guideline:

other: no data

Principles of method if other than guideline:

The information does not come from a test report and the minimum fields cannot be filled in.

GLP compliance:

not specified

Type of method:

other: no data

Key result

Water solubility:

77 g/L

Temp.:

20 °C

Remarks on result:

other: pH unknown

Conclusions:

77 g/L at 20°C

Executive summary:

According to the 'Handbook of Environmental Fate and Exposure Data for Organic Chemicals, Volume II, Solvents', the water solubility of Tributyl borate is 77 g/L (at 20°C).

No further experimental details are reported in the handbook.

Reference 3

Endpoint:

water solubility

Type of information:

other: experimental study on hydrolysis product n-Butanol

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: data from well documented publication

Reason / purpose for cross-reference:

reference to same study

Qualifier:

equivalent or similar to guideline

Guideline:

EPA OPPTS 830.7860 (Water Solubility Generator Column Method)

Principles of method if other than guideline:

Details of the generator column:
- It consists of a 20-cm section of 6-mm o.d. Pyrex tubing joined to a short section of 9-mm o.d. Pyrex tubing. The 6-mm o.d. section of the column was packed with 100-120 mesh Chromosorb W-HP (solid support) which was held in place by two plugs of silanized glass wool. The column was thermostated at 25.0 ± 0.1 °C by pumping water from a constant-temperature bath through a jacket enclosing column.
- The column was coated with a liquid solute by pulling approximately 2 mL of the liquid through the clean, dry support with gentle suction.
- The aqueous phase of the solute was generated by pumping water into the inlet of the coated generator column either by using a minipump or by means of a water reservoir using compressed air at 5 psi.
- Analysis of the aqueous phase from the pure solute coated column yielded the aqueous solubility.

GLP compliance:

not specified

Type of method:

other: Generator Column Method

Water solubility:

63.3 g/L

Temp.:

25 °C

Remarks on result:

other: pH unknown

Details on results:

The reported water solubility is an average of at least three measurements.

Conclusions:

63.2 g/L at 25°C

Executive summary:

According to a well documented publication (Tewari Y.B. et al, 1982), the water solubilty of Tributyl borate is 63.2 g/L (at 25°C). The measurement was performed with a modified Generator Column Method.

Description of key information

Study scientifically not necessary because tributyl borate is rapidly hydrolyzed to boric acid and n-butanol in the presence of water:

- water solubilty of boric acid: 49.2 g/L (at 20°C)

- water solubilty of n-butanol: 77 g/L at 20°C (handbook data) and 63.2 g/L at 25°C (data from publication); key value (arithmetic mean of the two available values) ca. 70 g/L at 20°C

Key value for chemical safety assessment

Water solubility:

70 g/L

at the temperature of:

20 °C