Cyclohexanone, peroxide

Biodegradation in water: screening tests

Link to relevant study record(s)

Reference

Endpoint:

biodegradation in water: ready biodegradability

Type of information:

experimental study

Adequacy of study:

key study

Study period:

1989

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: A well performed guideline study but certificate of analyses is not attached to the report.

Qualifier:

according to guideline

Guideline:

OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)

Deviations:

yes

Remarks:

instead of an effluent/extract/mixture activated sludge was used as inoculum. Ammonium chloride was omitted from the medium to prevent nitrification.

GLP compliance:

yes (incl. QA statement)

Oxygen conditions:

aerobic

Inoculum or test system:

sewage, predominantly domestic, non-adapted

Details on inoculum:

Secondary activated sludge was obtained from the RZWI Nieuwgraaf in Duiven 1st of September 1989. This is an activated sludge plant treating predominantly domestic wastewater.

Duration of test (contact time):

28 d

Initial conc.:

2 mg/L

Based on:

act. ingr.

Parameter followed for biodegradation estimation:

O2 consumption

Reference substance:

acetic acid, sodium salt

Remarks:

.

Key result

Parameter:

% degradation (O2 consumption)

Value:

92

Sampling time:

28 d

Results with reference substance:

The percentage biodegradation of the reference compound was 87% in day 28.

Percentage biodegradation of the test substance and sodium acetate in the closed bottle test

Time (days)	5	15	28
Test substance (% BOD/ThOD)	69	85	92
Sodium acetate (% BOD/ThOD)	73	83	87

The data in the table shows that the substance should be classified as readily biodegradable based on the final biodegradation at day 28 (92%) The biodegradation in day 5 (69%) shows that the substance passes the 10-day window.

 

Validity criteria fulfilled:

yes

Interpretation of results:

readily biodegradable

Conclusions:

The test substance is readily biodegradble.

Executive summary:

This closed bottle (OECD 301D) guideline study performed in 1989, shows that cyclohexanone peroxide is readily biodegrable, passing the 10 -day window. The minor deviation mentioned in the material and method part of the RSS, is not considered to effect the result.

Description of key information

The test substance is classified as readily biodegradable based on data from an OECD 301 D test. 

Key value for chemical safety assessment

Biodegradation in water:

readily biodegradable

Additional information

One guideline study on biodegradation in water is availble for cyclohexanone peroxide. The study was conducted in 1989, in accordance with OECD 301D, and the result is expressed as the oxygen consumption (BOD/ThOD). The study showed that the biodegradation of cyclohexanone peroxide was 92% in day 28. Therefore, cyclohexane peroxide is classified as readily biodegradble.