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Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment

Data source

Reference
Reference Type:
publication
Title:
Die sedative und hypnotische Wirkung des 1-Äthinyl-cyclohexyl-allophanat-(1)
Author:
Keil, Werner; Muschaweck, Roman; Rademacher, Erika
Year:
1954
Bibliographic source:
Arzneimittel-Forschung, Vol.4, pp. 477-9

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
not further specified
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
3-methylpent-1-en-3-ol
EC Number:
213-044-2
EC Name:
3-methylpent-1-en-3-ol
Cas Number:
918-85-4
Molecular formula:
C6H12O
IUPAC Name:
3-methylpent-1-en-3-ol
Details on test material:
- Name of test material (as cited in study report): 3-methyl-1-Penten-3-ol

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
olive oil
No. of animals per sex per dose:
50 animals total
Control animals:
not specified

Results and discussion

Effect levels
Key result
Sex:
not specified
Dose descriptor:
LD50
Effect level:
1 152 mg/kg bw
Based on:
not specified

Applicant's summary and conclusion

Interpretation of results:
Category 4 based on GHS criteria