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Physical & Chemical properties

Flammability

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Administrative data

Endpoint:
self-heating substances / mixtures
Type of information:
experimental study
Adequacy of study:
key study
Study period:
17 - 19 October 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
other: UN Recommendations on the TRANSPORT OF DANGEROUS GOODS: Manual of Tests and Criteria
Version / remarks:
Rev. 6 (2015)
Deviations:
no
Qualifier:
according to
Guideline:
other: VDI 2263 Sheet 1 Grewer Oven
Version / remarks:
1990
Deviations:
no
GLP compliance:
yes (incl. certificate)

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
impurity
Test material form:
solid: particulate/powder
Details on test material:
Batch No.: 10004539
Storage at room temperature approx. 20°C

Results and discussion

Self-heating substances / mixturesopen allclose all
Key result
Test procedure:
other: Grewer oven
Remarks:
pure test item
Result:
other: An endothermic process was detected starting at a temperature of approx. 220 °C, which can be assigned to the melting of the test item.
Remarks on result:
other: no self-heating observed at atmospheric pressure up to its melting temperature of approx. 220 °C.
Key result
Test procedure:
other: Grewer oven
Remarks:
test item in mixture with Kieselguhr
Max. temp. reached:
330
Result:
other: temperature increase was observed starting at 230°C
Key result
Test procedure:
other: Grewer oven
Remarks:
test item in mixture with Kieselguhr
Max. temp. reached:
600
Result:
other: temperature increase was observed starting at 350°C

Any other information on results incl. tables

In the investigation of self-ignition in the Grewer Oven for the pure test item an endothermic process was detected starting at a temperature of approx. 220 °C, which can be assigned to the melting of the test item. No further thermal processes could be observed up the maximum test temperature of approx. 420 °C. After the measurement a swollen black residue remained in the wire basket.

For the test item in mixture with Kieselguhr an endothermic process was detected starting at a temperature of approx. 220 °C, which can be assigned to the melting of the test item. The endothermic effect is directly followed by an exothermic process starting at a temperature of approx. 230 °C that led to a maximum temperature of approx. 330 °C (corresponding oven temperature 240 °C). A further exothermic effect was observed starting at a temperature of 350 °C, which led to a maximum temperature of approx. 600 °C (corresponding oven temperature 410 °C).

Applicant's summary and conclusion

Interpretation of results:
not classified based on GHS criteria
Conclusions:
The pure test item Adenosine (CAS no. 58-61-7) indicated no self-heating at atmospheric pressure up to its melting temperature of approx. 220 °C.
On the basis to the results of the tests on the self-ignition in the Grewer Oven the test item is classified as follows:
UN Transport Regulation: The test item is not classified as self-heating substance in class 4, division 4.2 according to the UN Transport Regulation.
GHS / CLP Regulation EC 1272/2008 Annex 1: 2.11: The test item is not classified as self-heating substance according to GHS/CLP Regulation EC 1272/2008 Annex 1: 2.11, respectively.


Executive summary:

The pure test item Adenosine (CAS no. 58-61-7) indicated no self-heating at atmospheric pressure up to its melting temperature of approx. 220 °C.  

On the basis to the results of the tests on the self-ignition in the Grewer Oven the test item is classified as follows:  

UN Transport Regulation: The test item is not classified as self-heating substance in class 4, division 4.2 according to the UN Transport Regulation.

GHS / CLP Regulation EC 1272/2008 Annex 1: 2.11: The test item is not classified as self-heating substance according to GHS/CLP Regulation EC 1272/2008 Annex 1: 2.11, respectively.