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EC number: 280-055-7
CAS number: 82864-58-2
and group rnean body weight (bw) of animals treated at 2000 mg/kg bw of
the test substance
clinical observation of animals treated at 2000 mg/kg bw of the test
necropsies of animals treated at 2000 mg/kg bw of the test substance
The study was carried out to assess acute
toxicity following a single oral administration to rats of the test
substance according to the OECD guideline 423. Wistar rats (Rattus
norvegicus) were selected and maintained under controlled
environmental conditions. Based on individual body weight, dosing of the
test substance was calculated in mg/kg body weight (bw). Two groups of
three female rats received 2000 mg/kg bw. Animals were observed for 14
At the end of this period, no mortality or
signs of evident toxicity were observed. Gross pathology examination was
performed on all tested animals. No macroscopic alterations were
observed in any of the major organs of the examined animals. Under the
test conditions, the LD50 was found to be greater than 2000 mg/kg bw.
Therefore, the test substance is not acutely toxic via the oral route.
LD50 > 2000 mg/kg bw
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