Registration Dossier

Administrative data

Key value for chemical safety assessment

Genetic toxicity in vitro

Description of key information

Based on the evaluation of the Ames test, the substance is considered not mutagen.

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (negative)

Additional information

Justification for classification or non-classification

The test results performed on similar substance showed the following results:

negative for strains TA1535 and TA98

slightly mutagenic for strain TA100

mutagenic for strain TA1537 and Escherichia Coli

the test item was non-mutagenic for V79 cells with and without metabolic activation.

Based on the evaluation reported in the attachment of the endpoint, the substance should be considered as not mutagen.