1-hydroxy-4-(p-toluidino)anthraquinone

Partition coefficient

Link to relevant study record(s)

Reference

Endpoint:

partition coefficient

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

study well documented, meets generally accepted scientific principles, acceptable for assessment

Qualifier:

according to guideline

Guideline:

other: Measurements of Octanol and Water solubility of Pigments (2006), carried out by ETAD Member companies. Data ownership is with ETAD.

Version / remarks:

January 12, 2005

Deviations:

no

Principles of method if other than guideline:

WATER
About 5 mg of the test sample were suspended in 30 ml water (bi dest.) in a sample flask (standard flask for the Büchi Rack R-24, volume 30 ml (Art.-No. 038469)) and were shaken for two hours at 30°C (+/- 2°C) on a “Büchi Syncore Polyvap” (laboratory shaking machine) with 400 rpm. Then shaking was continued at ambient temperature (24 – 25°C) for 70 hours, followed by filtration through a 0.05 μm membrane filter (Fa. Schleicher und Schuell, NC 05, Ref.-No.: 402110) (on the filter there remained a residue of not dissolved colorant).
The resulting clear solution was measured by UV-vis spectrometry and the absorption was determined at 583 nm. The concentration of the sample could be determined by applying the Lambert-Beer rule. A calibration curve of Solvent Violet 13 in DMSO (Merck, für die Spektroskopie “Uvasol”, Bestell-Nr.: 1.02950.2500) was used for that purpose.
The determination was repeated for three times.

OCTANOL
About 20 mg of the test sample were suspended in 30 ml octanol (Aldrich, spectrophotometric grade) in a sample flask (standard flask for the Büchi Rack R-24, volume 30 ml (Art.-No. 038469)) and were shaken for two hours at 30°C (+/- 2°C) on a “Büchi Syncore Polyvap” (laboratory shaking machine) with 400 rpm. Then shaking was continued at ambient temperature (24 – 25°C) for 70 hours, followed by filtration through a 0.2 μm membrane filter (Fa. Schleicher und Schuell, TE 35, Ref.-No.: 411411) and then through two 0.2 μm membrane filters (Fa. Schleicher und Schuell, TE 35, Ref.-No.: 411411) (on the filter there remained a residue of not dissolved colorant).
The resulting clear solution was measured by UV-vis spectrometry and the absorption was deter-mined at 585 nm. The concentration of the sample could be determined by applying the Lam-bert-Beer rule. A calibration curve of Solvent Violet 13 in DMSO (Merck, für die Spektroskopie “Uvasol”, Bestell-Nr.: 1.02950.2500) was used for that purpose.
The determination was repeated for three times.

GLP compliance:

no

Type of method:

flask method

Partition coefficient type:

octanol-water

Specific details on test material used for the study:

Purity: 100 % (pure)
Trade name: Solvent Violet 13
Batch No.: 0832B
CLAS Order No: 06-06078

Analytical method:

photometric method

Type:

log Pow

Partition coefficient:

4.26

Temp.:

25 °C

Remarks on result:

other: pH not reported

Details on results:

Solubilities of the test item measured at ambient temperature (24-25 °C):
- In water: 0.93 mg/L
- In octanol: 170 mg/L

Based on the calibration curve of the test item in DMSO (Merck, "Uvasol”) the concentration of the sample was determined by applying the Lambert-Beer rule.

Individual results:

Water

	Absorption (d = 10 cm)	µg/L
a1	0.001719	10.1
a2	0.002142	11.3
a3	0.000401	6.6

Octanol

	Absorption (d = 10 cm, dilution 1:50)	g/L
a1	0.1245	0.17
a2	0.1269	0.17
a3	0.1349	0.18

Conclusions:

The partition coefficient (logPow) of Solvent Violet 13 was estimated to be 4.26 at 25 °C.

Executive summary:

The partition coefficient (logPow) of Solvent Violet 13 was estimated to be 4.26 based on solubilities in water (0.93 mg/L) and octanol (170 mg/L) measured at ambient conditions (24-25 °C).

Description of key information

The partition coefficeint (logPow) for Solvent Violet 13 was estimated to be 4.26 at 25 °C.

Key value for chemical safety assessment

Log Kow (Log Pow):

4.26

at the temperature of:

25 °C

Additional information

The estimation of the partition coefficeint (logPow) was based on the solubilities for Solvent Violet 13 in water (0.0093 mg/L) and octanol (170 mg/L) measured at ambient conditions (24-25 °C).