1,2-benzisothiazol-3(2H)-one

GHS

General Information

Implementation:

EU

Type of classification:

self-classification

Remarks:

Aquatic classification is based on the most sensitive trophic group. Algae were the most sensitive trophic level with a 72-hour E_rC₅₀of 0.11 mg BIT/L.

This value is below 1 mg/L, thus Acute Category 1 is applied. Additionally the 0.1 < EC₅₀≤ 1.0 mg/L, therefore an M-factor of 1 is prescribed.

BIT did not fulfill the strict conditions of ready biodegradability tests to be considered readily biodegradable. On inherent biodegradability tests, BIT was also not considered inherently biodegradable. In aquatic systems with estuarine and sea water, BIT can be degraded rapidly with half-lives at 12ºC of 2-3 days in estuarine water and 5-12 days in sea water. In sandy loam soils the resulting half-lives were 9-14 hours.This means the substance is demonstrated to be ultimately degraded in a surface water simulation test with a half-life of < 16 days (corresponding to a degradation of >70 % within 28 days); thus it can be considered that BIT is rapidly degradable.

There are adequate chronic toxicity data available. The algae demonstrated to be the most sensitive trophic level regarding long-term effects with

a 72 -hour NOEC of 0.0403 mg BIT/L. This value is < 0.1 mg/L, thus Chronic Category 2 is applied.

Related composition

Related composition:

1,2-benzisothiazolin-3(2H)-one

1,2-benzisothiazolin-3(2H)-one

Classification

Physical hazards

Explosives

Reason for no classification:

data conclusive but not sufficient for classification

Flammable gases and chemically unstable gases

Reason for no classification:

data conclusive but not sufficient for classification

Aerosols

Reason for no classification:

data conclusive but not sufficient for classification

Reason for no classification:

hazard class not assessed

Oxidising gases

Reason for no classification:

data conclusive but not sufficient for classification

Gases under pressure

Reason for no classification:

data conclusive but not sufficient for classification

Flammable liquids

Reason for no classification:

data conclusive but not sufficient for classification

Flammable solids

Reason for no classification:

data conclusive but not sufficient for classification

Self-reactive substances and mixtures

Reason for no classification:

data conclusive but not sufficient for classification

Pyrophoric liquids

Reason for no classification:

data conclusive but not sufficient for classification

Pyrophoric solids

Reason for no classification:

data conclusive but not sufficient for classification

Self-heating substances and mixtures

Reason for no classification:

data conclusive but not sufficient for classification

Substances and mixtures which in contact with water emit flammable gases

Reason for no classification:

data conclusive but not sufficient for classification

Oxidising liquids

Reason for no classification:

data conclusive but not sufficient for classification

Oxidising solids

Reason for no classification:

data conclusive but not sufficient for classification

Organic peroxides

Reason for no classification:

data conclusive but not sufficient for classification

Corrosive to metals

Reason for no classification:

data lacking

Desensitized explosives

Reason for no classification:

data conclusive but not sufficient for classification

Health hazards

Acute toxicity - oral

Hazard category:

Acute Tox. 4

Hazard statement:

H302: Harmful if swallowed.

Acute toxicity - dermal

Reason for no classification:

data conclusive but not sufficient for classification

Acute toxicity - inhalation

Reason for no classification:

data conclusive but not sufficient for classification

Skin corrosion / irritation

Hazard category:

Skin Irrit. 2

Hazard statement:

H315: Causes skin irritation.

Serious eye damage / eye irritation

Hazard category:

Eye Damage 1

Hazard statement:

H318: Causes serious eye damage.

Respiratory sensitisation

Reason for no classification:

data lacking

Skin sensitisation

Hazard category:

Skin Sens. 1

Hazard statement:

H317: May cause an allergic skin reaction.

Aspiration hazard

Reason for no classification:

data conclusive but not sufficient for classification

Reproductive toxicity

Reason for no classification:

data conclusive but not sufficient for classification

Effects on or via lactation

Reason for no classification:

data conclusive but not sufficient for classification

Germ cell mutagenicity

Reason for no classification:

data conclusive but not sufficient for classification

Carcinogenicity

Reason for no classification:

data conclusive but not sufficient for classification

1. Specific target organ toxicity - single (STOT-SE)

Reason for no classification:

data conclusive but not sufficient for classification

1. Specific target organ toxicity - repeated (STOT-RE)

Reason for no classification:

data conclusive but not sufficient for classification

Environmental hazards

Hazardous to the aquatic environment (acute / short-term)

Hazard category:

Aquatic Acute 1

Hazard statement:

H400: Very toxic to aquatic life.

Hazardous to the aquatic environment (long-term)

Hazard category:

Aquatic Chronic 2

Hazard statement:

H411: Toxic to aquatic life with long lasting effects.

M-Factor acute:

1

M-Factor chronic:

1

Hazardous to the ozone layer

Reason for no classification:

data conclusive but not sufficient for classification

Labelling

Signal word:

Danger

Hazard pictogram

GHS07: exclamation mark

GHS05: corrosion

GHS09: environment

Hazard statements

H302: Harmful if swallowed.

H315: Causes skin irritation.

H318: Causes serious eye damage.

H317: May cause an allergic skin reaction.

H400: Very toxic to aquatic life.

H411: Toxic to aquatic life with long lasting effects.

Precautionary statements

P273: Avoid release to the environment.

P280: Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

P301+P312: IF SWALLOWED: Call a POISON CENTER/doctor/... if you feel unwell.

P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

P333+P313: If skin irritation or rash occurs: Get medical advice/attention.

P501: Dispose of contents/container to ...

P501: Dispose of contents/container in accordance with local/ regional/national/international regulation.