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EC number: 306-621-6 | CAS number: 97338-28-8
Quantitative determination of the analyte:
Flow rate 25 mL/h
Volume of combined fractions [mL]
Test substance [µg/L]
Flow rate 50 mL/h
Internal standard: 2.13 µg/L each fraction
Determination of the water solubility at a flow rate of 25 mL/h yielded values in a range from 1.15 µg/L to 4.23 µg/L and at a flow rate of 12.5 mL/h from 0.36 µg/L to 3.33 µg/L. In contradiction to the guideline, the concentrations differ by more than ±30%. This is however due to the low solubility of the test item. Therefore a larger difference is also considered acceptable.
Calculation of the water solubility was performed by the means of five succesive fractions after achieving a plateau (denoted by "+" in the table above; the discarded fractions are denoted by "-"). Mean values: 1.41 µg/L for the flow rate of 25.0 mL/h and 1.37 µg/L for the flow rate of 12.5 mL/h. The reported value of 1.39 µg/L is a formal mean value of the two; the water solubility ranges between 0.73 and 2.14 µg/L.
The calibration curve fits over a range from 0.426 µg/L to 21.320 µg/L. A quadratic fit was used; r² = 0.999.
1.39 µg/L at 20 °C, pH 6.3 (OECD 105)
The water solubility of the substance was determined using column elution method. The determined solubility range was 0.73 -2.14 µg/L. The solubility is very low.
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