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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2017-2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method A.8 (Partition Coefficient - Shake Flask Method)
Version / remarks:
May 31, 2008
Qualifier:
according to guideline
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Version / remarks:
July 27, 1995
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7550 (Partition Coefficient, n-octanol / H2O, Shake Flask Method)
Version / remarks:
August 1996
GLP compliance:
yes
Type of method:
flask method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
1,1'-[methylenebis(sulphonyl)]diethylene
EC Number:
221-909-0
EC Name:
1,1'-[methylenebis(sulphonyl)]diethylene
Cas Number:
3278-22-6
Molecular formula:
C5H8O4S2
IUPAC Name:
(ethenesulfonyl)methanesulfonylethene
Test material form:
solid: particulate/powder
Details on test material:
white crystalline powder

Study design

Analytical method:
high-performance liquid chromatography
mass spectrometry

Results and discussion

Partition coefficientopen allclose all
Type:
Pow
Partition coefficient:
>= 0.27 - <= 0.28
Temp.:
19.8 °C
pH:
6.6
Type:
log Pow
Partition coefficient:
>= -0.6 - <= -0.5
Temp.:
19.8 °C
pH:
6.6
Details on results:
The analysed concentration of the stock solution was 0.113 g/L. Based on this the nominal quantity of the test item in the test samples was 0.227 mg. The recoveries were determined according to this value.
The log Pow values were within the criterion range of ± 0.3 log units. The Pow and log Pow of the test item are given as the mean value of all measurements.
No test item was detected in the pre-treated samples from the blank mixture.

Applicant's summary and conclusion

Conclusions:
The shake flask method at neutral pH was applied for the determination of the partition coefficient (Pow) of CH02241.
The Pow value of the test item was 2.7 * 10^-1. It corresponds with a log Pow value of -0.6.