Registration Dossier
Registration Dossier
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EC number: 231-744-6 | CAS number: 7718-98-1
Toxicity to birds
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
Two entries were reported for toxicity to birds:
- The first one is a publication from Cervantes, 1985, where vanadium content of 0, 5, 10 or 20 ppm were given to male chicks from one day old during 4 weeks. Supplementing the diet with 10 or 20 ppm vanadium significantly reduced mean body weight, feed intake and feed efficiency. 5 mg/kg diet was determined as a NOEL for this study.
- The second one is a literature search completed according to the Eco-SSL guidance (U.S. EPA, 2003) which remained 36 papers containing data for avian test species. These papers were reviewed and data were extracted and scored according to the Eco-SSL guidance. Within the 36 reviewed papers, there were 132 results for biochemical, behavioural, physiology, pathology, reproduction, growth, and survival effects that had a Data Evaluation Score of >65 (sufficient to derive the Toxicity Reference Value).
The no-observed adverse effect (NOAEL) values for growth and reproduction are used to calculate a geometric mean NOAEL. A geometric mean of the NOAEL values for growth and reproduction was calculated at 1.19 mg vanadium/kg bw/day.
Toxicity to birds is not required for this dossier due to tonnage band but were referenced for knowledge purpose and showed that it is not necessary to go ahead with testing.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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