Registration Dossier
Registration Dossier
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EC number: 926-987-6 | CAS number: -
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
Data source
Reference
- Reference Type:
- other: prediction
- Title:
- Unnamed
- Year:
- 2 016
Materials and methods
Test guideline
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- QSAR
Test material
- Reference substance name:
- (8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione - 2,3,5,6-tetrachlorobenzene-1,4-diol (1:1)
- EC Number:
- 926-987-6
- Molecular formula:
- C22H28O33.C6H2Cl4O2
- IUPAC Name:
- (8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione - 2,3,5,6-tetrachlorobenzene-1,4-diol (1:1)
Constituent 1
- Specific details on test material used for the study:
- Canrenone
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 1 120 mg/kg bw
- Remarks on result:
- other: prediction
Applicant's summary and conclusion
- Interpretation of results:
- Category 4 based on GHS criteria
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