Registration Dossier
Registration Dossier
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EC number: 243-019-1 | CAS number: 19395-39-2
Toxicity to reproduction
Administrative data
- Endpoint:
- toxicity to reproduction
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Report date:
- 2015
Materials and methods
- Principles of method if other than guideline:
- Leadscope FDA Model Applier
- GLP compliance:
- no
Test material
- Reference substance name:
- α-phenylpiperidine-2-acetamide
- EC Number:
- 243-019-1
- EC Name:
- α-phenylpiperidine-2-acetamide
- Cas Number:
- 19395-39-2
- Molecular formula:
- C13H18N2O
- IUPAC Name:
- 2-phenyl-2-(piperidin-2-yl)acetamide
Constituent 1
Test animals
- Species:
- rat
- Sex:
- male/female
Administration / exposure
- Route of administration:
- oral: unspecified
Results and discussion
Results: P0 (first parental generation)
Effect levels (P0)
- Dose descriptor:
- other: alert
- Sex:
- male/female
- Basis for effect level:
- other: Negative (Little reliability)
- Remarks on result:
- not measured/tested
- Remarks:
- Effect level not specified Generation not specified (migrated information)
Overall reproductive toxicity
- Reproductive effects observed:
- not specified
Applicant's summary and conclusion
- Conclusions:
- The NEGATIVE prediction of reproductive toxicity on rat male/female for c-racemate was assessed with little reliability.
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