Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 932-164-2 | CAS number: -
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
Chromosome abberation test:
All vehicle controls had frequencies of cells with aberrations within the range expected for normal human lymphocytes.
All the positive control treatments gave significant increases in the frequency of cells with aberrations indicating the satisfactory performance of the test and of the activity of the metobolising system.
The substance induced no significant increases in the frequency of cells with aberrations or polyploid cells. The substance was shown to be non-clastogenic to human lymphocytes in vitro.
Reverse mutation assay (Ames test):
No significant increase in the number of revertant colonies was recorded for any of the bacterial strains with any dose of the substance either with or without metabolic activation. The substance was found to be non-mutagenic under the conditions of this test.
Mouse Micronucleus Test:
The test material was considered to be non-genotoxic under the conditions of the test.
Short description of key information:
A Reverse mutation assay, Chromosome abberation test and Mouse micronucleus test showed no mutagenic effects.
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
Based on the above stated assessment of the two in vitro and one in vivo genetic toxicity studies, the test item may be regarded as non-genotoxic, therefore no classification according to Council Directive 2001/59/EC (28th ATP of Directive 67/548/EEC) or according to CLP (Regulation (EC) No 1272/2008 of the European Parliament and of the Council) as implementation of UN-GHS in the EU is needed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
