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EC number: 932-164-2
CAS number: -
Studies were done according to corresponding guidelines and under GLP conditions.
This study was entitled "Primary skin irritation/corrosion study with
the substance in the rabbit (4-hour semi-occlusive application)".
The purpose of this study was to assess the possible irritation or
corrosion potencial of the substance when a single dose was placed on
the skin of rabbits. Under the conditions of this study, the substance
resulted in well defined or severe erythema and slight or moderate
oedema in the three animals. The skin irritation had not resolved within
the study period and no corrosive effect occurred on the skin in all
The substance resulted in a primary irritation index of 5.3 (severely
irritating) when applied to intact rabbit skin.
DRAIZE SCORE CALCULATION
Calculations for EEC classification
This study was entitled "Acute eye irritation/corrosion study with the
substance in the rabbit". This study was carried out in accordance with
OECD Guideline No.405, "Acute eye irritation/corrosion.
Under the conditions of this study, the substance resulted in adverse
effects on the conjuctivae in all three animals, which had resolved
within 7 days. Ocular corrosion was not observed in any of the animals.
The substance was considered not irritant to the rabbit eye according to
GHS and to CLP
The substance is irritating for skin. The substance is mildly irritating
to eyes, but not sufficient for classification.
- skin irritation / corrosion:
Based on the above stated assessment of the skin irritation / corrosion
test, the results show that the test item is irritating to skin and
needs to be classified as "R38 Irritating to skin" according to Council
Directive 2001/59/EC (28th ATP of Directive 67/548/EEC) or as Category
2, "Warning - H315: Causes skin irritation" according to CLP (Regulation
(EC) No 1272/2008 of the European Parliament and of the Council) as
implementation of UN-GHS in the EU.
- eye irritation / corrosion:
Based on the above stated assessment of the eye irritation test, the
results show that the test item is not eye irritating and does not need
to be classified according to Council Directive 2001/59/EC (28th ATP of
Directive 67/548/EEC) or according to CLP (Regulation (EC) No 1272/2008
of the European Parliament and of the Council) as implementation of
UN-GHS in the EU.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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