Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 208-736-6 | CAS number: 540-10-3
Endpoint summary
Administrative data
Description of key information
Additional information
The target substance hexadecyl palmitate (CAS 540-10-3) is a long-chain aliphatic ester with a high estimated log Kow (> 10.0, QSAR, Vega version 1.1.3 - three models: Meylan/Kowwin version 1.1.4, MLogP version 1.0.0, ALogP version 1.0.0), which suggests a high potential for bioaccumulation.
However, since the substance has low water solubility (< 0.846 µg/L, at 20 °C, OECD 105) and is readily biodegradable, no chronic exposure, relevant uptake or bioaccumulation in aquatic organisms is expected. In the case of uptake by fish, the substance is expected to be rapidly metabolized via enzymatic hydrolysis into fatty acids and fatty alcohols, which are also expected to metabolize satisfactorily in aquatic organisms. From literature it is well known that these hydrolysis products will be effectively metabolized and excreted in fish (Heymann, 1980; Lech & Bend, 1980; Lech & Melancon, 1980; Murphy & Lutenske, 1990; Sand et al., 1973).
Therefore, in accordance with Annex XIII of Regulation (EC) No 1907/2006 it is concluded that the substance has no potential for bioaccumulation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
