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Toxicity to microorganisms

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Description of key information

IC50 (3 h) > 320 mg/l

Key value for chemical safety assessment

EC50 for microorganisms:
320 mg/L

Additional information

The toxicity to microorganism potential is investigated in two studies conducted on the SImilar Substance 01. The complete hypothesis and justification for the read across approach has been attached in section 13.

In the key study, the toxicity to activated sludge was determined in a 3-hours respiration inhibition test according to the OECD Guideline No. 209.

The test substance concentrations tested were 320, 100, 32 and 10 mg/l. The reference substance, 3,5-Dichlorophenol was tested in concentrations of 32, 10 and 3.2 mg/l.

The reported results are:

IC50 (3 h) of the test substance: > 320 mg/l

IC20 (3 h) of the test substance: 123 mg/l

IC50 (3 h) of the reference substance 3,5-Dichlorophenol: 11 mg/l

The second test, although the report is not detailed, confirms the results found previously.