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Ecotoxicological information

Short-term toxicity to fish

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Link to relevant study record(s)

Description of key information

TL50(96h) = 446 mg/l

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
446 mg/L

Additional information

The evaluation of toxicity to fish of the substance has been based on studies conducted on the Similar Substance 01. The complete hypothesis and justification for the read across approach has been attached in section 13.

Three short-term toxicity tests to fish are available. The toxicity potential is investigated with three different specie (Lepomis macrochirus, Leuciscus idus and Salmo trutta). All tests were performed according to internal methods.

Despite the key study was not carried out according to a OECD Guideline and the test substance purity was ca. 55 %, it has been chosen as a benchmark study for the safety assessment, because it turns out to be the most detailed and complete test among those available.

Healthy bluegill sunfish fingerlings were used as test animals. The percentages of survival were recorded for 5 concentrations and the untreated control. In addition, the main behavioral reactions and their duration, following the dose administration, were recorded.

The reported result is expressed in terms of four - day medium tolerance limit, but in this case it can be compared to a LC50 value, considering that mortality was the discriminating factor in the study.

The TL50 values, reported in the two other studies, were estimated after an observation period of 48h and they are very close to the result of the first test.