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EC number: 946-901-0 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Justification for type of information:
- Data comes from an online compilation using secondary data sources. There is no experimental study reference, however data provided from validated QSAR.
- Qualifier:
- according to guideline
- Guideline:
- other: ECOSAR
- Version / remarks:
- 1.11
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 0.681 mg/L
- Validity criteria fulfilled:
- not specified
- Conclusions:
- LC50 of daphnia is 0.681 mg/L for acetate lavandulyle.
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Justification for type of information:
- Data comes from an online compilation using secondary data sources. There is no experimental study reference, however data provided from validated QSAR.
- Qualifier:
- according to guideline
- Guideline:
- other: ECOSAR
- Version / remarks:
- 1.11
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 0.82 mg/L
- Validity criteria fulfilled:
- not specified
- Conclusions:
- LC50 of daphnia is 0.820 mg/L for acetate linalyle.
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Justification for type of information:
- Data comes from an online compilation using secondary data sources. There is no experimental study reference, however data provided from validated QSAR.
- Qualifier:
- according to guideline
- Guideline:
- other: ECOSAR
- Version / remarks:
- 1.11
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 13.38 mg/L
- Validity criteria fulfilled:
- not specified
- Conclusions:
- LC50 of daphnia is 13.380 mg/L for borneol.
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Justification for type of information:
- Data comes from an online compilation using secondary data sources. There is no experimental study reference, however data provided from validated QSAR.
- Qualifier:
- according to guideline
- Guideline:
- other: ECOSAR
- Version / remarks:
- 1.11
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 0.019 mg/L
- Validity criteria fulfilled:
- not specified
- Conclusions:
- LC50 of daphnia is 0.019 mg/L for caryophyllene.
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Justification for type of information:
- Data comes from an online compilation using secondary data sources. There is no experimental study reference, however data provided from validated QSAR.
- Qualifier:
- according to guideline
- Guideline:
- other: ECOSAR
- Version / remarks:
- 1.11
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 3.903 mg/L
- Validity criteria fulfilled:
- not specified
- Conclusions:
- LC50 of daphnia is 3.903 mg/L for lavandulol.
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Justification for type of information:
- Data comes from an online compilation using secondary data sources. There is no experimental study reference, however data provided from validated QSAR.
- Qualifier:
- according to guideline
- Guideline:
- other: ECOSAR
- Version / remarks:
- 1.11
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 4.698 mg/L
- Validity criteria fulfilled:
- not specified
- Conclusions:
- LC50 of daphnia is 4.698 mg/L for linalol.
Referenceopen allclose all
Description of key information
Based on a weight of evidence approach, the acute toxicity of lavandin oil heavy fraction to aquatic invertebrates (daphnia) can be estimated using adequate toxicity data of major constituents, greater than 1% in the mixture. Six constituents were considered representing more than 85% of the UVCB substance.These data are summarized in the table below:
Constituent names | CAS nr | LC50 daphnia 48h (mg/L) | source |
acetate linalyle (67%) | 115 -95 -7 | 0.82 | ECOSAR V1.11 |
borneol (5%) | 507 -70 -0 | 13.38 | ECOSAR V1.11 |
acetate lavandulyle (5%) | 25905-14-0 | 0.681 | ECOSAR V1.11 |
linalol (3%) | 78-70-6 | 4.698 | ECOSAR V1.11 |
caryophyllene (3%) | 87-44-5 | 0.019 | ECOSAR V1.11 |
lavandulol (2%) | 58461-27-1 | 3.903 | ECOSAR V1.11 |
using additivity formula mentionned in CLP regulation 1272/2008 in section 4.1.3.5.2., the LC50 daphnia for the lavandin oil heavy fraction is estimated at 2.92 ml/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 2.92 mg/L
Additional information
At 2.92 mg/L for EC50 daphnia 48h, the UVCB substance is classified as H411 (cat 2).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

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