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EC number: 946-901-0 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Justification for type of information:
- Data comes from an online compilation using secondary data sources. There is no experimental study reference, however data provided from validated QSAR.
- Qualifier:
- according to guideline
- Guideline:
- other: ECOSAR
- Version / remarks:
- 1.11
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 0.681 mg/L
- Validity criteria fulfilled:
- not specified
- Conclusions:
- LC50 of daphnia is 0.681 mg/L for acetate lavandulyle.
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Justification for type of information:
- Data comes from an online compilation using secondary data sources. There is no experimental study reference, however data provided from validated QSAR.
- Qualifier:
- according to guideline
- Guideline:
- other: ECOSAR
- Version / remarks:
- 1.11
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 0.82 mg/L
- Validity criteria fulfilled:
- not specified
- Conclusions:
- LC50 of daphnia is 0.820 mg/L for acetate linalyle.
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Justification for type of information:
- Data comes from an online compilation using secondary data sources. There is no experimental study reference, however data provided from validated QSAR.
- Qualifier:
- according to guideline
- Guideline:
- other: ECOSAR
- Version / remarks:
- 1.11
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 13.38 mg/L
- Validity criteria fulfilled:
- not specified
- Conclusions:
- LC50 of daphnia is 13.380 mg/L for borneol.
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Justification for type of information:
- Data comes from an online compilation using secondary data sources. There is no experimental study reference, however data provided from validated QSAR.
- Qualifier:
- according to guideline
- Guideline:
- other: ECOSAR
- Version / remarks:
- 1.11
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 0.019 mg/L
- Validity criteria fulfilled:
- not specified
- Conclusions:
- LC50 of daphnia is 0.019 mg/L for caryophyllene.
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Justification for type of information:
- Data comes from an online compilation using secondary data sources. There is no experimental study reference, however data provided from validated QSAR.
- Qualifier:
- according to guideline
- Guideline:
- other: ECOSAR
- Version / remarks:
- 1.11
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 3.903 mg/L
- Validity criteria fulfilled:
- not specified
- Conclusions:
- LC50 of daphnia is 3.903 mg/L for lavandulol.
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Justification for type of information:
- Data comes from an online compilation using secondary data sources. There is no experimental study reference, however data provided from validated QSAR.
- Qualifier:
- according to guideline
- Guideline:
- other: ECOSAR
- Version / remarks:
- 1.11
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 4.698 mg/L
- Validity criteria fulfilled:
- not specified
- Conclusions:
- LC50 of daphnia is 4.698 mg/L for linalol.
Referenceopen allclose all
Description of key information
Based on a weight of evidence approach, the acute toxicity of lavandin oil heavy fraction to aquatic invertebrates (daphnia) can be estimated using adequate toxicity data of major constituents, greater than 1% in the mixture. Six constituents were considered representing more than 85% of the UVCB substance.These data are summarized in the table below:
| Constituent names | CAS nr | LC50 daphnia 48h (mg/L) | source |
| acetate linalyle (67%) | 115 -95 -7 | 0.82 | ECOSAR V1.11 |
| borneol (5%) | 507 -70 -0 | 13.38 | ECOSAR V1.11 |
| acetate lavandulyle (5%) | 25905-14-0 | 0.681 | ECOSAR V1.11 |
| linalol (3%) | 78-70-6 | 4.698 | ECOSAR V1.11 |
| caryophyllene (3%) | 87-44-5 | 0.019 | ECOSAR V1.11 |
| lavandulol (2%) | 58461-27-1 | 3.903 | ECOSAR V1.11 |
using additivity formula mentionned in CLP regulation 1272/2008 in section 4.1.3.5.2., the LC50 daphnia for the lavandin oil heavy fraction is estimated at 2.92 ml/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 2.92 mg/L
Additional information
At 2.92 mg/L for EC50 daphnia 48h, the UVCB substance is classified as H411 (cat 2).
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