1-(4-METHOXYPHENYL)-4-(4-NITROPHENYL)PIPERAZINE

Explosiveness

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

explosive properties of explosives

Type of information:

experimental study

Adequacy of study:

key study

Study period:

23 February 2017 - 24 March 2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.14 (Explosive properties)

Deviations:

no

GLP compliance:

yes

Specific details on test material used for the study:

- Batch n°: I17AB0392
- Expiration date: 05 February 2019
- Analytical purity: 100% (base titration), 97.6% (GC purity)
- Storage condition of test material: at room temperature

Key result

Test series:

other: EU Regulation (EC) 440/2008, Annex Part A test A14

Method:

other: EC A.14, BAM Fallhammer

Parameter:

limiting impact energy (J)

Value:

40

Result:

result is considered "-" (negative)

Remarks:

Substance exhibited no reaction at 40 J.

Key result

Test series:

other: EU Regulation (EC) 440/2008, Annex Part A test A14

Method:

other: EC A.14, BAM Friction

Parameter:

limiting load (N)

Value:

360

Result:

result is considered "-" (negative)

Remarks:

The substance exhibited no reaction at 360 N.

Key result

Test series:

other: EU Regulation (EC) 440/2008, Annex Part A test A14

Method:

other: EC A.14, Koenen Tube

Parameter:

limiting diameter (mm)

Value:

6

Result:

result is considered "-" (negative)

Remarks:

The substance did not exhibit an explosion during any of the tests

Interpretation of results:

other: Not explosive

Conclusions:

Based on the results of the test performed according to the EC A.14 method, it is concluded that the test substance, JNJ-1806792-AAA (T001325), is not explosive.

Reference 2

Endpoint:

explosive properties of explosives

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

other: The test is performed according to EC guideline with some small deviations. However, there is no information on purity of the substance.

Qualifier:

according to guideline

Guideline:

EU Method A.14 (Explosive properties)

Deviations:

yes

Remarks:

1)The weight of the falling hammer is 5 kg and dropped from 0.8 m, however, the energy applied is the same as guideline, 40 J or 40 Nm. 2) In contrast to the EC guideline aluminium foil is used to pack the substance. 3) Ten tests are performed.

GLP compliance:

not specified

Parameter:

sensitiveness to impact: impact energy (J)

Remarks on result:

negative (not further specified)

Remarks:

If all tests according to Lütolf method are negative, powder can be considered not shock sensitive as reference substance meta-dinitrobenzene is not shock sensitive in similar conditions (although not tested simultaneously in this study)

RESULTS:

10 times negative, not shock sensitive (sensitivity > 39.2 Nm)

Interpretation of results:

GHS criteria not met

Conclusions:

The test substance is not shock sensitive (sensitivity > 39.2 Nm).

Reference 3

Endpoint:

explosive properties of explosives

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance contains chemical groups associated with explosive properties which include oxygen, but the calculated oxygen balance is less than - 200

Description of key information

Based on a GLP study performed according to the EU Method A.14 (K1, Livingston, 2017) applying the BAM Fallhammer test, the BAM friction test and the Koenen Tube test which gave a negative result and the oxygen balance which is lower than -200, it was concluded that the test substance T001325 is not explosive.

Key value for chemical safety assessment

Explosiveness:

non explosive

Additional information

From a not assignable supporting study (K4, PSC, 1986) according to the EC A.14 method with deviations, the test substance was determined to be not shock sensitive (sensitivity > 39.2 Nm).

Justification for classification or non-classification

Since a GLP study performed according to the EU Method A.14 (K1, Livingston, 2017) applying the BAM Fallhammer test, the BAM friction test and the Koenen Tube test turned out negative and the oxygen balance is determined to be lower than -200, it was concluded that the test substance is not explosive.