Registration Dossier

Administrative data

Hazard for aquatic organisms

Hazard for air

Hazard for terrestrial organisms

Hazard for predators

Additional information

Aquatic toxicity

QSAR results are available to assess the aquatic toxicity of the registered substance.

 

To assess the short-term toxicity to aquatic invertebrate and algae, two reliable QSAR results are available.The QSAR predictions (iSafeRat holistic approach v1.7) has been validated to be compliant with the OECD recommendations for QSAR modeling (OECD, 2004) and predict the ecotoxicological values which would be expected when testing the substance under experimental conditions in a laboratory following OECD Guidelines. The ecotoxicological predictions were determined using a validated QSAR for the Mode of Action in question, (MOA 1, non-polar narcosis). This QSAR is based on validated data for training sets for which the concentrations of the test substance had been determined by chemical analyses over the test period. According to these predictions, the 48h-EC50 value for aquatic invertebrates, based on mobility, was determined to be 1.0 mg/L (95% CL: 0.99 - 1.1 mg/L), and the 72 -h ErC50 value for algae, based on growth rate, was determined to be 0.92 mg/L (95% CL: 0.86 - 1.0 mg/L). The substance falls within the applicability domain of the model.

Environmental fate and pathways

The registered substance is considered as not readily biodegradable at 28 and 60 days. The substance can be considered as potentially Persistent (P) or very Persistent (vP) in the environment.

Also, the registered substance has a log Kow value at 4.8, the substance is considered as potential bioaccumulative according to CLP (> 4.0) and PBT criteria (> 4.5).

Conclusion on classification

No harmonised classification is available on the registered substance

0.1 < lowest E(L)C50 value < 1 mg/L; not readily biodegradable; logKow=4.8.

Classification according to the criteria of Annex I of the Regulation (EC) No 1272/2008 (CLP):The registered substance is classified as Aquatic Acute 1 and Aquatic Chronic 1 for the environment.