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Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2016-03-11
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)
Version / remarks:
12 May 1981
Deviations:
no
GLP compliance:
yes
Type of method:
Laser scattering/diffraction
Type of distribution:
volumetric distribution
Percentile:
D10
Mean:
8.42 µm
St. dev.:
0.02
Key result
Percentile:
D50
Mean:
49.87 µm
St. dev.:
0.35
Percentile:
D90
Mean:
240.49 µm
St. dev.:
0.2
No.:
#1
Size:
< 2 µm
Distribution:
1.75 %
No.:
#2
Size:
>= 2 - <= 200 µm
Distribution:
85.7 %
No.:
#3
Size:
> 200 µm
Distribution:
12.6 %

Particle Size Distribution






























 



Measurement 1


[µm]



Measurement 2


[µm]



Average


[µm]



D10 (v, 0.1)



8.434



8.406



8.42



D50 (v, 0.5)



50.173



49.576



49.87



D90 (v, 0.9)



240.312



240.665



240.49



 


Distribution in Fractions






























Fraction


[µm]



Measurement 1


[%]



Measurement 2


[%]



Average


[%]



Up to 2 µm



1.75



1.75



1.8



2 -200 µm



85.65



85.68



85.7



Over 200 µm



12.59



12.58



12.6


Conclusions:
The D50 percentile were determined as D50 = 49.87 µm.
Executive summary:

A study was conducted according to OECD Test Guideline 110 to determine the particle size distribution using the laser diffraction method with dry dispersion. Two measurements have been performed. The D10, D50 and D90 percentile were determined as D10 = 8.42 µm, D50 = 49.87 µm and D90 = 240.49 µm, respectively. 1.8 % of the total sample volume consisted of particles which were smaller than 2 µm, 85.7 % of the sample volume consisted of particles with sizes between 2 and 200 µm and 12.6 % of the sample volume consisted of particles larger than 200 µm.

Description of key information

TheD50 apercentile was determined as D50 = 49.87 µm (reference 4.5-1).

Additional information

A study was conducted according to OECD Test Guideline 110 to determine the particle size distribution using the laser diffraction method with dry dispersion. Two measurements have been performed. The D10, D50 and D90 percentile were determined as D10 = 8.42 µm, D50 = 49.87 µm and D90 = 240.49 µm, respectively. 1.8 % of the total sample volume consisted of particles which were smaller than 2 µm, 85.7 % of the sample volume consisted of particles with sizes between 2 and 200 µm and 12.6 % of the sample volume consisted of particles larger than 200 µm.