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Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
abstract

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1976
Report date:
1976

Materials and methods

Principles of method if other than guideline:
No information available
GLP compliance:
no
Remarks:
pre-GLP
Test type:
other: No information available

Test material

Constituent 1
Chemical structure
Reference substance name:
Reaction products of 6-hydroxy-5-nitrosonaphthalene-2-sulfonic acid, chelated with iron (3+), sodium salts.
EC Number:
943-973-5
Molecular formula:
not available being an UVCB substance
IUPAC Name:
Reaction products of 6-hydroxy-5-nitrosonaphthalene-2-sulfonic acid, chelated with iron (3+), sodium salts.

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
water
Details on oral exposure:
VEHICLE
- Concentration in vehicle: 10 - 50 %.


Control animals:
not specified
Details on study design:
- Duration of observation period following administration: 14 days.

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
ca. 8 200 mg/kg bw
Based on:
test mat.
Other findings:
Dyspnea, apathy, prone position, agressiveness, tumbling, slowed movements, diarrhea, feces urine stained green, general condition was bad, organs and connective tissue were stained.

Applicant's summary and conclusion

Interpretation of results:
other: not classified as harmful/toxic according to the CLP Regulation (EC) No.1272/2008
Conclusions:
LD50=. 8200 mg/kg b.w.
Executive summary:

Method

The acute oral toxicity of the substance was evaluated after the exposure of rats to 10 -50 % acqueous suspensions of the substance. The animals were observed for 14 days after the administration of the substance.

Observations:

During the test the following findings were observed: dyspnea, apathy, prone position, agressiveness, tumbling, slowed movements, diarrhea, feces urine stained green, general condition was bad, organs and connective tissue were stained.

Results:

The LD50 was found to be ca. 8200 mg/kg b.w.