Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

EC50 (48h, Daphnia magna) > 100 mg/L (nominal)

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
100 mg/L

Additional information

The following data was obtained for the Similar Substance 01. It is expected that the Target substance will present similar effect levels to daphnia. Justification for the use of a read-across approach is provided in Section 13 of IUCLID.

The acute toxicity of the test item to Daphnia magna under static conditions was investigated in an experimental study, according to the OECD Guideline 202 screening test (2004). Groups of 40 Daphnia magna (20 per tank) were exposed to test item concentrations of 1 mg/L (low-concentration group), 10 mg/L (mid-concentration group) and 100 mg/L (high concentration group) for a duration of 48 hours. Daphnia were monitored for immobility at 24 and 48 hours. A negative control group of 60 Daphnia (20 per tank) were tested in parallel.

No immobilisation was observed in control or treatment tanks after 24 hours. After 48 hours, the three control groups experienced 5 %, 10 % and 5 % immobilisation; 5 % and 10 % immobilisation occurred in groups exposed to 1 mg/L and 10 mg/L; 20 % immobilisation occurred in the groups exposed to 100 mg/L. No analytical measurement of test item concentration was performed throughout the test. Based on Daphnia immobilisation, the 48-hour EC50value was found to be greater than 100 mg/L based on nominal concentrations.