Registration Dossier
Registration Dossier
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EC number: 944-062-5 | CAS number: -
Endpoint summary
Administrative data
Description of key information
EC50 (48h) invertebrate Daphnia: 8.18 mg/L
EC50 (7d) aquatic plants Lemna minor: > 100 mg/L (frond number, dry weight)
NOEC (7d) aquatic plants Lemna minor: 25.1 mg/L (frond number, dry weight)
Additional information
Invertebrate acute toxicity
The median effect concentration (EC50) and the no-effect concentration (NOEC) of the substance to Daphnia magna were investigated under static exposure conditions over a period of 48 h, following the guideline OECD 202 and EU C.2, as WSFs (water soluble fractions).
The investigated concentrations were 300, 136, 62.0, 28.2 and 12.8 mg/L loading rate of the test item, corresponding to 219, 99.8, 45.3, 20.6 and 9.37 mg/L of the active ingredient.
The EC50 Daphnia magna at 24h was found to be 18.6 mg/L, the EC50 Daphnia magna at 48h was found to be 8.18 mg/L based on the geometric mean (GM) of the measured concentrations of the active ingredient.
Aquatic Plants toxicity
The inhibitory effects of the substance to the duckweed Lemna minor were investigated over a period of 7 days, based on the frond number and biomass (dry weight), following the guideline OECD 221 and the EU C.26.
The HPLC measurements indicated that the test item concentrations decrease and do not remain in the recommended 80-120% range of the nominal concentration. Even though 50% effects on the growth rate of the frond number could not be attained with the maximal concentration tested here (100 mg/L active ingredient), the limited effects observed at this concentration as well as the flat dose-response curve allow to estimate that the 7-day ErC50 on the duckweed Lemna minor for the endpoint frond number is >100 mg/L active ingredient.
50% effects on the growth rate of the dry weight could not be attained with the maximal concentration tested here (100 mg/L active ingredient). However, the limited effects observed at this concentration as well as the flat dose-response curve allow to estimate that the 7-day ErC50 on the duckweed Lemna minor for the endpoint dry weight is >100 mg/l active ingredients.
The NOEC (7d) aquatic plants Lemna minor was found to be 25.1 mg/L (frond number, dry weight)
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