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EC number: 254-409-6 | CAS number: 39300-88-4 Extractives and their physically modified derivatives. It is a product which may contain resin acids and their esters, terpenes, and oxidation or polymerization products of these terpenes. Caesalpinia, Leguminosae.
At the end of the 9 readings of the induction phase, the average score of each subject (Cumulative irritation index CII) is calculated by adding the scores obtained for each readings and by dividing this sum by the actual number of readings.The irritating potential of the product is estimated by calculating the mean of the reactions observed
during the induction phase in order to obain the Mean cumulative Irritation Inde (MCII). the obtained index allows to arbitrarily classify the studied product according to the following scale:
A possible reaction during the induction or challenge phase is assessed from 0 to 3 according to ICDRG (International Contact Dermatitis Research Group). During the Challenge phase, the reading is done 30 minutes after patch-tests removal and 48 hours later. The sensitizing potential of the product is assessed by the readings on D37 and D39 according to the following criteria reaction++ or +++ in the absence of added irritation phenomenon. The presence of only one case of active sensitization or controlateral
side leads to the conclusion "Potentially sensitizing product".
Under these study conditions, no reaction ++ nor +++ was observed, so the test item can be considered non sensitizing.
A panel of 110 male and female human volunteers participated in a repeat insult patch test in which a test product applied to the back of the subjects under occlusive patches. 105 subjects completed the study. During the induction or challenge phase, no skin reactions were observed. The test item showed a score of 0.01. It can thus be considered as non-irritating.
No reaction ++ nor +++ was observed, so the product can be considered as non-sensitizing.
Under these study conditions, the product can be considered non-irritating and non-sensitizing
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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