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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Reference
Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Reference:
Composition 0
Principles of method if other than guideline:
48 hour acute toxicity
GLP compliance:
not specified
Test material information:
Composition 1
Test organisms (species):
Daphnia magna
Test type:
not specified
Water media type:
freshwater
Hardness:
52 mg/l CaCO3
Details on test conditions:
Static
Key result
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
ca. 16.8 mg/L
Conc. based on:
element

 Water hardness mg/l CaCO3 48 hr EC50 µg chromium/l
 52 16800 
99   27400
110   26300
 195  51400
215   58700
Conclusions:
In considering the relative low toxicity of the oxalate ion, and the fact that this will precipitate as calcium oxalate in natural water, the toxicity of the substance is considered to be directly in relation to the chromium III ions.
The EC50 of Cr 3+ is considered to be 16.8 mg/l, which relates to ca 50 mg/l expressed as chromium oxalate.
Executive summary:

In an unpublished study reported in this review article, the acute toxicity of chromium nitrate to Daphnia magna at 5 water hardnesses was measured and the 48-hr EC50 ranged from 16.8 mg chromium/L in soft water to 57.8 mg chromium/L in hard water.

Description of key information

In considering the relative low toxicity of the citrate ion, the toxicity of the substance is considered to be directly in relation to the chromium III ions.

The EC50 of Cr 3+ is considered to be 16.8 mg/l, which relates to ca 77 mg/l expressed as chromium citrate.

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
50 mg/L

Additional information