4-chloroformylphthalic anhydride

Flash point

Administrative data

Endpoint:

flash point of flammable liquids

Data waiving:

study technically not feasible

Justification for data waiving:

the study does not need to be conducted because the flash point is only relevant to liquids and low melting point solids

Justification for type of information:

JUSTIFICATION FOR DATA WAIVING
According to IU Section 4.2, the melting point of the test substance is 66°C. Therefore it is still solid at the upper classification threshold of 60°C, based on CLP criteria.
The classification of the test item for flammable properties is based on the UN N1 test (see 4.13).

Cross-reference

Cross-reference 1

Reason / purpose for cross-reference:

data waiving: supporting information

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From 15 July 2015 to 30 September 2015

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Remarks:

Study performed according to recognized international guidelines. No deviation from the guideline was observed in the study

Reason / purpose for cross-reference:

reference to same study

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reference to same study

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reference to same study

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reference to same study

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reference to same study

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Version / remarks:

July 27, 1995

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Version / remarks:

Regulation (EC) 440/2008

Deviations:

no

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7200 (Melting Point / Melting Range)

Version / remarks:

March 1998

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

other: differential scanning calorimetry

Specific details on test material used for the study:

4-chloroformylphthalic anhydride

Key result

Melting / freezing pt.:

66 °C

Preliminary test:

The test substance was heated at a rate of 20°C/minute from 25°C to 342°C. At this point, 70% weight loss of the test substance was observed.

Main test:

Three experiments have been performed, under nitrogen and at atmospheric pressure:

Experiment	1	2	3
Sample amount (mg)	3.78	3.02	3.42
Crucible	Aluminium, pierced	Aluminium, pierced	Aluminium, pierced
Initial temperature (°C)	25	-25	-25
Rate (°C/min)	20	20	20
Temperature 2 (°C)	---	100	---
Rate (°C/min)	---	-5	---
Temperature 3 (°C)	---	-50	---
Rate (°C/min)	---	20	---
End temperature (°C)	316	150	150

In experiment 1, an endothermic peak between 50°C and 100°C was observed. The extrapolated onset temperature of the peak could not be determined since it was observed within 2 minutes from the start of the experiment. The effect was most likely obtained due to melting of the test item.

To investigate this peak, a repeated heating cycle was applied in the experiment 2, starting at a lower temperature.

With the first heating phase, the extrapolated onset temperature of the melting peak was 66.25°C.

During cooling, no effects were observed which were due to crystallization of the test substance.

With the second heating, an exothermic peak between 0°C and 50°C was observed. The effect was obtained due to crystallization of the test item. Second heating in combination with cooling provides enough time for test item to crystalize at lower temperatures. Then, a further endothermic effect, due to melting of the test item, was recorded with an extrapolated onset temperature of 65.67°C. This value was not used for calculation of the melting temperature, since it was obtained by melting of non-original test substance. After the experiment, a colourless molten residue remained in the sample container.

Experiment 3 was performed to determine the duplicate melting temperature of the test item. The extrapolated onset of the melting peak was 66.10°C. After the experiment, a colourless molten residue remained in the sample container.

The melting temperature was determined as the average melting temperature obtained from Experiment 2 (66.25°C) and Experiment 3 (66.10°C).

Conclusions:

The melting point of the test item is 66°C.

Executive summary:

The melting point of the test item was determined with Differential Scanning Calorimetry (DSC), according to recognized guidelines (OECD Guideline 102, EU Method A.1 and EPA OPPTS 830.7200) and under GLP. No deviations from the guidelines have been observed during the test.

Two consistent determinations, under nitrogen atmosphere, provided an average melting point of 66°C.

Cross-reference 2

Reason / purpose for cross-reference:

data waiving: supporting information

Reference

Endpoint:

flammable solids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From 15 July 2015 to 30 September 2015

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Reason / purpose for cross-reference:

reference to same study

Reason / purpose for cross-reference:

reference to same study

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reference to same study

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reference to same study

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reference to same study

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reference to same study

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reference to same study

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reference to same study

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reference to same study

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reference to same study

Qualifier:

according to guideline

Guideline:

UN Manual of Tests and Criteria: Test N.1 (Test method for readily combustible solids)

Version / remarks:

UN no. ST/SG/AC.10/11/Rev.5, 2009

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.10 (Flammability (Solids))

Version / remarks:

Regulation EC no. 440/2008

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Specific details on test material used for the study:

4-chloroformylphthalic anhydride

Key result

Test procedure:

burning rate test: preliminary screening test

Remarks on result:

substance does not ignite and propagate combustion either by burning with flame or smouldering along 200 mm of the powder train within the 2 minutes test period

In contact with the flame of the gas burner the test item melted, and turned into a black residue. White smoke was observed. After removal of the ignition source, no propagation of combustion of the test item was observed.

Interpretation of results:

not classified based on GHS criteria

Conclusions:

The test item does not propagate combustion in the preliminary test.
Therefore it is NOT considered as a flammable solid, based on GHS and CLP criteria.

Executive summary:

The flammability of the test item was determined according to recognized guidelines (UN N.1, EU A.10)

and under GLP.

No deviation from the guidelines was observed during the test.

The test item did not propagate combustion in the preliminary test.

Therefore it is NOT considered as a flammable solid, based on GHS and CLP criteria.