Registration Dossier
Registration Dossier
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EC number: 603-316-2 | CAS number: 129050-27-7
Boiling point
Administrative data
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 08 February 2016 - 11 July 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 103 (Boiling point/boiling range)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.2 (Boiling Temperature)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7220 (Boiling Point / Boiling Range)
- Deviations:
- no
- Principles of method if other than guideline:
- During the preliminary test, the sample oven was heated to a temperature of 549°C instead of 550°C. Gathered information was sufficient for the execution of the main study.
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- differential scanning calorimetry
Test material
- Reference substance name:
- (1S)-2-(benzylamino)-1-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol
- EC Number:
- 603-316-2
- Cas Number:
- 129050-27-7
- Molecular formula:
- C18H20FNO2
- IUPAC Name:
- (1S)-2-(benzylamino)-1-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol
- Test material form:
- solid: particulate/powder
- Details on test material:
- - Name of test material (as cited in study reports): JNJ-17298957-AAA (T001592)
- Physical state: solid (powder)
- Appearance: White powder
Constituent 1
- Specific details on test material used for the study:
- - Batch n°: I15HB2929
- Analytical purity: 100% (Based on base titration assay)
- Expiration date: 14 Aug 2017
- Storage condition: at room temperature
Results and discussion
Boiling point
- Key result
- Atm. press.:
- 1 013.25 hPa
- Decomposition:
- yes
- Remarks:
- A beige molten residue remained in the sample container due to reaction and/or decomposition.
- Decomp. temp.:
- > 250 °C
- Remarks on result:
- other: Boiling of the test item was not observed below the temperature of decomposition and/or reaction, therefore the test item has no boiling temperature.
Any other information on results incl. tables
Boiling of the test item was not observed below the temperature of decomposition and/or reaction (> 250°C). Based on this, the test item has no boiling temperature.
Applicant's summary and conclusion
- Conclusions:
- The test item has no boiling temperature.
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