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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

LC50 (96 h) > 100 mg/L (nominal) for Oncorhynchus mykiss (OECD 203)

EC50 (48 h) > 100 mg/L (nominal) for Daphnia magna (OECD 202)

EC50 (72 h, growth rate) = 5.3 mg/L (mean measured) for Pseudokirchneriella subcapitata (OECD 201)

NOECr (72 h, growth rate) = 1 mg/L (nominal) for Pseudokirchneriella subcapitata (OECD 201)

EC50 (3 h, total, heterotrophic and nitrification respiration) > 1000 mg/L (nominal) for activated sludge (OECD 209)

NOEC (3 h, total, heterotrophic and nitrification respiration) ≥ 1000 mg/L (nominal) for activated sludge (OECD 209)

Additional information

The aquatic toxicity of 2-{2-chloro-4-mesyl-3-[(tetrahydrofuran-2-lmethoxy)methyl]benzoyl}cyclohexane-1,3-dione was tested in four studies with organisms of different trophic levels (M-446236-01-1 (2013); M-212589-01-1(2003); M-116272-01-1(2003); M-287714-01-1 (2007); M-570517-01-1; 2016). All studies were conducted under GLP and according to the respective OECD guidelines. The results of these tests are summarised in the table below:

Test species

Test system

Test duration (h)

Effect values (mg/L)

Reference

Oncorhynchus mykiss

Semi-static acute

96

LC50 > 100

2013; M-446236-01-1

Daphnia magna

Static acute

48

EC50 > 100

2003; M-212589-01-1

Pseudokirchneriella subcapitata

Static acute/chronic

72

ECr50 = 5.3

NOECr = 1.0

2003; M-116272-01-1

2007; M-287714-01-1

Respiration and nitrification inhibition test with activated sludge

Static acute/chronic

3

EC50 > 1000

NOEC ≥ 1000

2016; M-570517-01-1