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Environmental fate & pathways

Hydrolysis

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Description of key information

The test substance was shown to be hydrolytically stable at pH 4, 7, and 9 [t1/2 (25°C) > 1 year].

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Additional information

A GLP study according to the test method for the “Test on Hydrolyzability” of agricultural chemicals stipulated in the “Notification Concerning Test Data for Registration of Agricultural Chemicals” (12 Nohsan No. 8147) and the measurement method stipulated in the OECD Test Guideline 111 was conducted to determine the rate of hydrolysis in aqueous solution at pH values normally found in the environment (pH 4, 7 and 9) (M-398574-01-2; 2004).

A preliminary hydrolysis test was performed at 50 °C in aqueous solution at pH 4, 7 and 9. The mean residual rate of the test substance was at least 90% at all pH levels under the test conditions used in the present study (50 °C, 5 days). Therefore, the test substance was shown to be hydrolytically stable (t1/2 (25 °C) > 1 year). On the basis of the results from the preliminary test, no further work was conducted.