Registration Dossier
Registration Dossier
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EC number: 613-167-5 | CAS number: 6315-60-2
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Justification for type of information:
- QSAR prediction
- Guideline:
- other: REACH Guidance on (Q)SAR
- Principles of method if other than guideline:
- (Q)SAR
- Test organisms (species):
- other: Green algae
- Test type:
- other: (Q)SAR
- Water media type:
- freshwater
- Duration:
- 96 h
- Dose descriptor:
- EC50
- Effect conc.:
- 19.381 mg/L
- Dose descriptor:
- other: Chronic Value (ChV)
- Effect conc.:
- 5.959 mg/L
- Validity criteria fulfilled:
- yes
- Remarks:
- Aliphatic Amines: Maximum LogKow: 7.0 (Green Algae EC50) - 7.0 (Chronic Value)
- Conclusions:
- Estimated EC50 (96h) : 19 mg/L
Estimated Chronic Value : 5.9 mg/L
Intermediate substance is estimated to be harmful to aquatic algae with long lasting effects.
Reference
Description of key information
Short-term toxicity:
ECOSAR 1.11: Green Algae: EC50 (96h): 19.381 mg/L
Danish (Q)SAR Database: Pseudokirchneriella s. 72h EC50:
Battery: 24.26 mg/L
Leadscope: 41.93 mg/L
SciQSAR: 6.58 mg/L
Long-term toxicity:
Indicated results for chronic toxicity are "Chronic values" as obtained from ECOSAR 1.11
ECOSAR 1.11: Green Algae: ChV: 5.959 mg/L
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 19 mg/L
- EC10 or NOEC for freshwater algae:
- 5.9 mg/L
Additional information
NOEC could be estimated to around 4.2 mg/L (ChV/√2) as indicated in Practical Guide 5 - How to use and report (Q)SARs 3.0 (March 2016)
Intermediate substance is estimated to be harmful to aquatic algae with long lasting effects.
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