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Ecotoxicological information

Long-term toxicity to fish

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Endpoint:
long-term toxicity to fish, other
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction
Guideline:
other: REACH Guidance on (Q)SAR
Principles of method if other than guideline:
(Q)SAR
Test organisms (species):
no data
Test type:
other: (Q)SAR
Water media type:
freshwater
Duration:
32 d
Dose descriptor:
other: Chronic Value (ChV)
Effect conc.:
9.659 mg/L

ECOSAR Program (v1.11) Results:

See attachment in above summary: Aquatic toxicity - ECOSAR Program (v1.11) Results

Validity criteria fulfilled:
yes
Remarks:
Esters: Maximum LogKow: 8.0 (Chronic Value)
Conclusions:
Estimated Chronic Value : 9.6 mg/L
Intermediate substance is not estimated to be toxic to fish (Chronic toxicity).
Endpoint:
long-term toxicity to fish, other
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction
Guideline:
other: REACH Guidance on (Q)SAR
Principles of method if other than guideline:
(Q)SAR
Test organisms (species):
no data
Test type:
other: (Q)SAR
Water media type:
saltwater
Duration:
32 d
Dose descriptor:
other: Chronic Value (ChV)
Effect conc.:
20.722 mg/L

ECOSAR Program (v1.11) Results:

See attachment in above summary: Aquatic toxicity - ECOSAR Program (v1.11) Results

Validity criteria fulfilled:
yes
Remarks:
Esters: Maximum LogKow: 8.0 (Chronic Value)
Conclusions:
Estimated Chronic Value : 20.7 mg/L
Intermediate substance is not estimated to be toxic to fish (Chronic toxicity).

Description of key information

Indicated results are "Chronic values" as obtained from ECOSAR 1.11

Key value for chemical safety assessment

EC10, LC10 or NOEC for freshwater fish:
9.6 mg/L
EC10, LC10 or NOEC for marine water fish:
20.7 mg/L

Additional information

Lowest NOEC could be estimated to around 6.8 mg/L (ChV/√2) as indicated in Practical Guide 5 - How to use and report (Q)SARs 3.0 (March 2016)

Intermediate substance is not estimated to be toxic to fish (Chronic toxicity).