Registration Dossier

Administrative data

Endpoint:
bioaccumulation in aquatic species: fish
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
01 Oct - 27 Dec 1982
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1984
Report Date:
1984

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: MITI Guideline (Japan)
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder
Radiolabelling:
no

Test solutions

Vehicle:
not specified

Test organisms

Test organisms (species):
Oryzias latipes

Study design

Route of exposure:
aqueous
Justification for method:
aqueous exposure method used for following reason: water soluble substance
Test type:
static
Water / sediment media type:
natural water: freshwater
Total exposure / uptake duration:
8 wk

Test conditions

Reference substance (positive control):
not specified

Results and discussion

Bioaccumulation factoropen allclose all
Key result
Conc. / dose:
1 mg/L
Temp.:
20 °C
Type:
BAF
Value:
< 0.4 L/kg
Basis:
whole body w.w.
Calculation basis:
steady state
Conc. / dose:
0.1 mg/L
Temp.:
20 °C
Type:
BAF
Value:
< 4.4 L/kg
Basis:
whole body w.w.
Calculation basis:
steady state
Details on results:
48-h LC50 tested in parallel: >1000 mg/L

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
The BAF of the substance was determined at <0.4 L/kg after 8 weeks exposure time (1 mg/L) in the orange-red killifish. The substance has no potential to accumulate in organisms.