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Physical & Chemical properties

Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
experimental dates: 15 May to 07 June 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
The study was conducted according to an internationally recognised method, and under GLP, without deviation. The substance is adequately characterised. Therefore full validation applies.
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
23. Mar. 2006
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
Regulation (EC) N°440/2008, as modified by Reg.(EC) No 761/2009
Deviations:
no
GLP compliance:
yes (incl. certificate)
Remarks:
Landesamt für Umwelt, Wasserwirtschaft und Gewerbeaufsicht (inspected on 13 & 14 October 2014, 2010 / signed on 08 April 2015)
Type of method:
effusion method: Knudsen cell
Key result
Temp.:
25 °C
Vapour pressure:
0.81 Pa

Parameter

T

Mean P

1/T

log VP

Unit

K (°C)

Pa

1/K

log Pa

Values

303.2 (30.0)

1.02

3.2982E-03

0.0095

318.2 (45.0)

2.6

3.1427E-03

0.4064

333.2 (60.0)

4.5

3.0012E-03

0.6484

 

A graph with log VP vs. 1/T was plotted. Since the values were correlated by a linear relation, the data could be fitted by linear regression:

Slope = -2158.0

Intercept = 7.1468

Correlation Coefficient r = -0.9938

Coefficient of Determination r2 = 0.9875

The vapour pressures at 20°C and at 25°C were calculated from the regression equation (mean value, rounded for accuracy/SD):

 Vapour pressure at 20°C = 0.61 Pa

Vapour pressure at 25°C = 0.81 Pa

Conclusions:
Low volatility (based on volatility bands criteria for occupational exposure (Chesar / ECETOC TRA), << 500 Pa).
Executive summary:

The vapour pressure of the test substance was measured under GLP according to OECD 104 / EU A4 guideline, effusion method with Knudsen cell (weight loss).

Determinations were conducted at 30, 45 and 60 °C, with triplicate measurements for each of the four cells.

The vapour pressure at 25°C of the test item was extrapolated from the regression as 0.81 Pa.

Description of key information

Low volatility.

Key value for chemical safety assessment

Vapour pressure:
0.81 Pa
at the temperature of:
25 °C

Additional information

A fully reliable experimental study, conducted according to a recognized OECD/EC method and under GLP, is available. Therefore, it is considered as a key study, and the result is retained as key data.