Registration Dossier
Registration Dossier
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EC number: 500-039-8 | CAS number: 25322-69-4 1 - 4.5 moles propoxylated
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
An assessment of the PBT status of ‘propane-1,2-diol, propoxylated’ has been made using all available data. The information available suggests that the substance does not meet the PBT screening criteria as outlined in Annex XIII of Directive 2006/121/EC. Detailed analysis of each of the main components listed in chapter 1.2 of the IUCLID dossier are shown in the individual entries in this chapter. A summary of the PBT assessment is shown below.
Persistence
Manometric Respirometry tests (OECD 301F) showed that the structural analogues and constituents mono-, di and tripropylene glycol are ready biodegradable and that the higher order analogues tetra and pentapropylene glycol are inherently biodegradable. Therefore, polypropylene glycol can be regarded as biodegradable and thus not persistent.
Bioaccumulation
Based on the result of the octanol/water partition coefficient (log Kow of < 0.3 - 1.13), it is expected that ‘propane-1,2-diol, propoxylated’ has no bioaccumulative potential.
Toxicity
Experimental data on acute toxicity are available for the structural analogies and constituents di- and tripropylene glycol. All acute L(E) C50values are much higher than the screening criterion of 0.1 mg/l. ‘Propane-1,2-diol, propoxylated’ is not classified as being a CMR substance and there is no evidence that it is chronically toxic towards mammals. It can therefore be expected that ‘propane-1,2-diol, propoxylated’ is not toxic towards aquatic organisms
- Likely routes of exposure:
‘Propane-1,2-diol, propoxylated’ is not a PBT/vPvB substance, therefore the emission characterisation need not to be conducted.
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