Registration Dossier
Registration Dossier
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EC number: 813-845-2 | CAS number: 13780-04-6
Endpoint summary
Administrative data
Description of key information
NOEL oral rat subacute ≥ 841 mg Ca(H2PO3)2 /kg bw/day
Key value for chemical safety assessment
Repeated dose toxicity: via oral route - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- NOAEL
- 841 mg/kg bw/day
- Study duration:
- subacute
- Species:
- rat
Repeated dose toxicity: inhalation - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Repeated dose toxicity: inhalation - local effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Repeated dose toxicity: dermal - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Repeated dose toxicity: dermal - local effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Justification for selection of repeated dose toxicity via oral route - systemic effects endpoint:
Reliable GLP study for the analogue substance KH2PO3/K2HPO3.
Justification for classification or non-classification
Repeated oral toxicity
The substance is not classified orally toxic because it doesn't meet the classification criteria of the CLP regulation n. 1272/2008 on repeated exposure:
No oral repeated toxicity on organs was predicted up to 841 mg/kg bw/day for Calcium dihydrogenphosphite.
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