Registration Dossier

Ecotoxicological information

Toxicity to soil microorganisms

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
toxicity to soil microorganisms
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Reason / purpose:
read-across source
Test organisms (inoculum):
soil
Total exposure duration:
28 d
Nominal and measured concentrations:
1000 mg/kg
Duration:
28 d
Dose descriptor:
EC50
Effect conc.:
> 1 000 mg/kg soil dw
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
respiration rate
Duration:
28 d
Dose descriptor:
NOEC
Effect conc.:
1 000 mg/kg soil dw
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
respiration rate
Details on results:
The test material showed no significant effect on carbon transformation activity of soil micro-organisms at a test concentration of 1000 mg/kg over a 28-day period. The test material is therefore considered to have no long-term effect on carbon transformation in soil.
Conclusions:
The effect on the carbon transformation activity of soil micro-organisms was investigated over a 28 day period and gave an EC50 value of greater than 1000 mg/kg and a NOEC of 1000 mg/kg.

Description of key information

Soil micro-organism toxicity (carbon transformation): NOEC 1000 mg/kg
Soil micro-organism toxicity (nitrogen transformation): NOEC 1000 mg/kg

Key value for chemical safety assessment

Short-term EC50 for soil microorganisms:
1 000 mg/kg soil dw
Long-term EC10 or NOEC for soil microorganisms:
1 000 mg/kg soil dw

Additional information

OECD Guideline 216 (Soil Microorganisms: Nitrogen Transformation Test):

The effect on the nitrogen transformation activity of soil micro-organisms was investigated over a 28 day period and gave an EC50 value of greater than 1000 mg/kg and a NOEC of 1000 mg/kg.

OECD Guideline 217 (Soil Microorganisms: Carbon Transformation Test):

The effect on the carbon transformation activity of soil micro-organisms was investigated over a 28 day period and gave an EC50 value of greater than 1000 mg/kg and a NOEC of 1000 mg/kg.