Registration Dossier

Physical & Chemical properties

Water solubility

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
The study was conducted on 15 March 2016
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
not specified
GLP compliance:
not specified
Remarks:
Not conducted to specific GLP program, but conducted following the principles of GLP by expperienced and trained personnel using calibrated standards and instrumentation. Relevant SOPs followed, the results are deemed accurate for regulatory purposes
Type of method:
flask method
Specific details on test material used for the study:
Batch/Lot no. 3434.15 used
Key result
Water solubility:
> 0.283 - < 0.35 g/L
Conc. based on:
test mat. (dissolved fraction)
Loading of aqueous phase:
1 g/L
Incubation duration:
> 1 - < 3 d
Temp.:
30 °C
pH:
> 5.7 - < 5.9
Remarks on result:
other: average solubility = 0.321 g/L

RD14153 Water Solubility

Sample #   Sample added (g/L)  Equilibration time (days)  Measured (g/L)

 % average

 1  1.058  1  0.283  88
 2  1.096  1  0.287  89
 3  1.098  2  0.350  109
 4  1.084  2  0.352  110
 5  1.064  3  0.318  99
 6  1.012  3  0.338  105
       Average of samples 1 - 6  0.321  -
Conclusions:
The RD14153 material under test was analyzed in accordance with the guideline set forth in OECD 105, water solubility, shake flask method. the water solubility was 0.32 g/L
Executive summary:

The RD14153 material under test was analyzed in accordance with the guideline set forth in OECD 105, water solubility, shake flask method. the water solubility was 0.32 g/L

Description of key information

The RD 14153 material under test was analyzed in accordance with the guideline set forth in OECD 105, water solubility, shake flask method. the water solubility was 0.32 g/L

Key value for chemical safety assessment

Water solubility:
0.32 g/L
at the temperature of:
30 °C

Additional information