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EC number: 946-742-7 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 25 Nov - 24 Dec 2009
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
- Report date:
- 2010
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- N-[3-(dimethylamino)propyl] amides C18-22 (even numbered)
- IUPAC Name:
- N-[3-(dimethylamino)propyl] amides C18-22 (even numbered)
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): Cambridge Sewage Treatment Works, Cowley Road, collected 24 Nov 2009
- Pretreatment: Sieved to 850 µm, settled, decanted and resuspended using mineral media. Centrifuged at ca. 4000 rpm for ca. 10 minutes discarded the supernatant, re-suspended and centrifuged again at ca. 4000 rpm for ca. 10 minutes and discarded the supernatant. Dry sludge solids determination was conducted on the pellet produced
- Dry sludge solids: 5.7%
- Volume of mineral medium: 1.5 L per bioreactor
- Dry sludge solids in test: 0.03 g/L - Duration of test (contact time):
- 28 d
Initial test substance concentrationopen allclose all
- Initial conc.:
- > 39.4 - < 39.5 mg/L
- Based on:
- test mat.
- Initial conc.:
- 20 mg/L
- Based on:
- other: carbon
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- TEST SYSTEM
- Culturing apparatus: 2000 mL flasks filled with 1500 mL test medium
- Number of culture flasks/concentration: 2
- Details of trap for CO2 and volatile organics if used: Atmospheric air was pumped into the test system and scrubbed clean of carbon dioxide by passing over soda lime. The air continued into the test vessel where it collets any evolved carbon dioxide before moving into the carbon dioxide traps, each containing 200 mL of 0.05 M sodium hydroxide solution
- Other: The test solutions were stirred for the duration of the study
CONTROL AND BLANK SYSTEM
- Inoculum blank: 2 flasks
- Reference: 2 flasks
- Toxicity control: 1 flask
Reference substance
- Reference substance:
- acetic acid, sodium salt
Results and discussion
% Degradationopen allclose all
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 0
- Sampling time:
- 0 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 24
- Sampling time:
- 5 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 50
- Sampling time:
- 9 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 71
- Sampling time:
- 14 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 87
- Sampling time:
- 28 d
Any other information on results incl. tables
Table 1: Inorganic carbon (mg) in 200 mL NaOH
Time (days) |
Blank |
Reference |
Test chemical |
Toxicity control |
|||
1 |
2 |
1 |
2 |
1 |
2 |
||
2 |
2.52 |
2.54 |
10.82 |
9.24 |
4.01 |
3.44 |
14.00 |
5 |
2.17 |
2.06 |
8.17 |
8.09 |
9.25 |
7.21 |
13.17 |
7 |
1.13 |
1.05 |
3.49 |
3.73 |
5.35 |
5.03 |
6.23 |
9 |
0.94 |
0.80 |
2.76 |
2.81 |
4.10 |
5.84 |
5.38 |
14 |
1.62 |
1.48 |
4.54 |
5.44 |
6.97 |
8.77 |
9.85 |
19 |
0.85 |
0.84 |
2.49 |
2.61 |
3.73 |
3.78 |
5.12 |
23 |
0.63 |
0.51 |
2.00 |
2.14 |
2.17 |
2.29 |
3.81 |
28 |
1.24 |
0.59 |
1.42 |
2.06 |
1.26 |
1.46 |
2.15 |
29 |
0.65 |
1.84 |
1.69 |
2.30 |
1.17 |
0.33 |
1.48 |
29 |
2.56 |
1.47 |
3.13 |
2.44 |
1.60 |
1.24 |
6.33 |
Table 2: Cumulative inorganic carbon (mg) from test
Time (days) |
Reference |
Test chemical |
Toxicity control |
||
1 |
2 |
1 |
2 |
||
0 |
0.00 |
0.00 |
0.00 |
0.00 |
0.00 |
2 |
8.29 |
6.71 |
1.48 |
0.91 |
10.27 |
5 |
14.34 |
12.68 |
8.61 |
6.00 |
15.21 |
7 |
16.74 |
15.32 |
12.87 |
9.94 |
16.25 |
9 |
18.63 |
17.26 |
16.10 |
13.91 |
17.16 |
14 |
21.62 |
21.15 |
21.52 |
21.13 |
19.14 |
19 |
23.26 |
22.91 |
24.40 |
24.06 |
20.50 |
23 |
24.69 |
24.48 |
26.00 |
25.78 |
22.08 |
28 |
25.19 |
25.62 |
26.34 |
26.32 |
22.87 |
29 |
25.63 |
26.67 |
26.26 |
25.40 |
23.60 |
29 |
26.74 |
27.09 |
25.84 |
24.62 |
28.51 |
Table 3: Percentage degradation
Time (days) |
Reference |
Test chemical |
Toxicity control |
||||
1 |
2 |
Mean |
1 |
2 |
Mean |
||
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
2 |
28 |
22 |
25 |
5 |
3 |
4 |
34 |
5 |
48 |
42 |
45 |
29 |
20 |
24 |
51 |
7 |
56 |
51 |
53 |
43 |
33 |
38 |
54 |
9 |
62 |
57 |
60 |
53 |
46 |
50 |
57 |
14 |
72 |
70 |
71 |
71 |
70 |
71 |
64 |
19 |
77 |
76 |
77 |
81 |
80 |
80 |
68 |
23 |
82 |
82 |
82 |
86 |
85 |
86 |
74 |
28 |
84 |
85 |
85 |
88 |
87 |
87 |
76 |
29 |
85 |
89 |
87 |
87 |
84 |
86 |
79 |
29 |
89 |
90 |
90 |
86 |
82 |
84 |
95 |
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
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