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Toxicological information

Additional toxicological data

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Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: This information was obtained from the public IUCLID 2000 CD-ROM. The original report has not been reviewed further. Assessment of data quality to current OECD standards is not possible and the study has therefore been assigned Reliability 4.

Data source

Reference
Reference Type:
publication
Title:
The effects of ethylene-1-hydroxy-1,1-diphosphonate on cellular transformation and organic matrix of the epiphyseal growth plate of the rat: a light microscopic and ultrastructural study
Author:
Larsson A and Larsson SE
Year:
1978
Bibliographic source:
Acta Pathologica et Microbiologica Scandinavia, SectA Pathology, 86, 211-224

Materials and methods

Type of study / information:
Type: other: effects on bone

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
not specified
Details on test material:
Substance name as cited in the report: HEDP-xNa

Results and discussion

Applicant's summary and conclusion