Registration Dossier

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

The following was provided as the key study for the endpoint Toxicity to aquatic algae and cyanobacteria:
Odersma. H, Hanstveir. A.O, & de Haan. H.P.M (2004) Dibutyltin bis (2-ethy1hexylmercaptoacetate) (CAS# 10584-98-2 DBT(EHMA)): Determination of the effect on the growth of the fresh water green alga Scenedesmus subspicatus. Testing Laboratory: TNO Physiological Sciences, Location Zeist, Utrechtsweg 48, P.O. Box 360, 3700 AJ Zeist, The Netherlands. Owner Company: Organotin Environmental Programme (ORTEP) Association Stabilizer. Report No.: 010.45228/01.30. Report date: 2004-06-02.
The study was assigned a reliability score of 2 and considered suitable for assessment. The study was performed in compliance with GLP and according to the guideline OECD 201.
A further study was provided as supporting information:
Grade R (1993) Growth Inhibition Test of Irgastab T 22 M to Green Algae (Scenedesmus subspicatus). Testing Laboratory: Ciba-Geigy Ltd. Product Safety Ecotoxicology, R-1066.P, CH-4002 Basel, Switzerland. Owner company: Ciba-Geigy Ltd, AD - Division, CH-4002 Basel, Switzerland. Report No.: 928292. Report date: 1993-04-26
The study was provided as supporting information only as the test material on which the study was performed contained 65% of the substance of interest. The study was assigned a reliability score of 2.

Key value for chemical safety assessment

Additional information

Odersma. H, Hanstveir. A.O, & de Haan. H.P.M (2004) was submitted as the key study to fulfil the data requirement. The study was performed in accordance with the OECD guideline 201, in compliance with GLP. The study was assigned a reliability score of 2 and considered reliable and adequate for assessment.The toxicity of dibutyltin bis (2-ethylhexylmercaptoacetate) to the fresh water green algaScenedesmus subspicatuswas determined in a 72-h growth inhibition. The NOEC was ≥120 µg Sn/L, equivalent to ≥646 µg DBT(EHMA)/L. The ErC50 value was >120 µg Sn/L, equivalent to >646 µg DBT(EHMA)/L. The EbC50 value was >120 µg Sn/L, equivalent to >646 µg DBT(EHMA)/L.

 

Grade R (1993) was provided as the supporting study. The study was performed in compliance with GLP to a good scientific standard; accordingly the study was assigned a reliability score of 2. The acute toxicity to Green Algae (Scenedesmus subspicatus) was assessed in a 72 hour Algal inhibition test. The final measured concentrations tested were 0, 0.19, 0.29, 0.63, 1.1 and 2.5 mg/L. The EC50 (48 h) found to be 0.56 mg/L with 95 % confidence limits of 0.44 and 0.70 mg/L.