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Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Link to relevant study record(s)

Description of key information

One study was available for assessment of the endpoint Long-term toxicity to aquatic invertebrates.
de Roode D.F. & de Haan H.P.M. (2004) 2-Ethylhexyl 4,4-dibutyl-10-ethyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate [Dibutyltin bis(2¬ethyl hexylmercaptoacetate), CAS. No. 10584-98-2]: Daphnia magna, reproduction test (semi-static). Testing laboratory: NOTOX B.V. Hambakenwetering 7 5231 DD 's-Hertogenbosch, The Netherlands. Owner company: Parametrix, Inc. 5808 Lake Washington Blvd. NE, Suite 200 WA Kirkland U.S.A.. Report No: TNO Study Number: 0200B4. Report date: 2004-09-06.
The study was conducted in compliance with GLP and to the guideline OECD 211.
The 21-Day LC50 (immobilisation) value, based on percentage of WAF at 100 mg/L for the parental Daphnia generation was determined as 65%
The 21-Day EC50 (reproduction) value based on percentage of WAF at 100 mg/L was 56%
According to Water solubility (Butler & White, 2010/key) is the water solubility of DBTE 3.58 mg/L. From this value 10% of WAF are epuivalent to 0.36 mg/L. So it is concluded the NOEC is 0.36 mg DBTE /L
The NOEC (overall) based on percentage of WAF at 100 mg/L was 10 %, on the basis that this was the highest test concentration no noticeable difference from the control daphnia.

Key value for chemical safety assessment

EC10, LC10 or NOEC for freshwater invertebrates:
0.36 mg/L

Additional information

de Roode D.F. & de Haan H.P.M. (2004) was provided as the key study for this endpoint. The study was performed in compliance with GLP and to the OECD guideline 211. According to Water solubility (Butler & White, 2010/key) is the water solubility of DBTE 3.58 mg/L. From this value 10% of WAF are epuivalent to 0.36 mg/L. So it is concluded the NOEC is 0.36 mg DBTE /L