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EC number: 300-346-5
CAS number: 93925-43-0
No mortality was recorded in any of the treatments.
The test substance is an organic compound with the element tin (Sn) in
its molecular structure. An ICP-MS method was developed for the
determination of the test substance based on the element Sn. Validation
of the analytical assay was carried out, however, it was found that the
accuracies on test samples prepared with the test substance were
inadequate. The ICP-MS method developed was considered to be the best
possible for the determination of the test substance:
- Oxygen and helium gas were used to remove the organic and
tetrahydrofuran (THF) content of the test substance and accuracy samples.
- The analytical sequence had a normal number of samples and the
instrument was cleaned prior to use.
- The substance must be dissolved in THF since it was not directly
soluble in (aqueous) strong acids such as HNO3.
According to the results obtained it was concluded that it is not
possible to use the ICP-MS method for quantification of test samples to
support physico-chemical- and (eco)toxicologal studies. Other analytical
techniques such as GC, HPLC and UV-Vis were not suitable for the
determination of the test substance due to its hydrophobic molecular
LL50 (96 h) > 100 mg/L (nominal, OECD 203)
One experimental study is available investigating the effects of the
substance to freshwater fish. The study was performed according to OECD
203 (GLP) with Cyprinus carpio under static conditions. Test solutions
were prepared as loading rates of 1.0, 10.0 and 100 mg/L by adding
appropriate amounts of the substance to test medium followed by 1 h
stirring, 40 min settling and siphoning off the soluble fraction to be
used for testing. All test solutions were clear and colorless throughout
the test. Analytical measurements were not possible to be conducted
since no suitable analytical method could be established (see also
IUCLID section 5.1.2). No mortality was recorded after 96 h resulting in
a LL50 (96 h) of > 100 mg/L (nominal). No behavioral abnormalities and
sub-lethal effects were observed during testing.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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