1-Methyl-4-[(trans,trans)-4'-propyl[1,1'-bicyclohexyl]-4-yl] -benzene

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

12-03.-26.06.2014

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Deviations:

no

GLP compliance:

no

Type of method:

differential scanning calorimetry

Remarks:

and capillary method

Key result

Melting / freezing pt.:

> 61 - < 177 °C

Atm. press.:

1 013 hPa

Decomposition:

no

Sublimation:

no

Two DSC-measurements in aluminium crucibles with a hole showed three endothermic effects in the temperature range of 60 - 75 °C, 105 - 115 °C and 170 - 185 °C. The onset temperature is derived from the intersection of the tangent line with the highest slope of the endothermic peak with the baseline. The corresponding onset temperatures of the three endothermic effects are shown in table 1. No onset temperatures can be clearly assigned to a melting process.

Table 1: DSC measurements

ID	Onset/ °C	Temperature range/ °C	Crucible
34309	60.96	60 -75	Aluminium with a hole
	108.05	105 - 115
	176.94	170 - 185
34308	61.22	60 - 75	Aluminium with a hole
	108.06	105 - 115
	177.33	170 - 185

Additional measurements with the capillary method were performed in order to clarify the results of the DSC measurements.

Table 2: Capillary measurements

Set point/ °C	Heating rate/ K/min	End point/ °C	Phase change/ °C	Phase change/ °C	Phase change/ °C
30	10	150	67	111	-
30	10	150	67	111	-
30	10	150	68	111	-
60	1	68	64	-	-
50	10	210	67	109	179

In the temperature range of 30 - 64 °C the test item appeared as unchanged white crystals. In the temperature range of 64 - 67 °C the test item changed into cloudy I waxy and partly melted (phase change of the liquid crystal). Above 109 - 111 °C the test item changed into a cloudy liquid (phase change of the liquid crystal). Above 179 °C the test item changed into a clear liquid (phase change of the liquid crystal, clearing point). Due to the results of the DSC measurements and the capillary measurements it is concluded that the test item has a melting range of 61 - 177 °C with the occurrence of at least one mesophase.

Conclusions:

The test item has a melting range of 61 - 177 °C.

Executive summary:

A study was conducted according to OECD TG 102 and Regulation (EC) No 440/2008 method A.1 to determine the melting point of the test item using differential scanning calorimetry and capillary tube method.

Two DSC-measurements in aluminium crucibles with a hole showed three endothermic effects in the temperature range of 60 - 75 °C, 105 - 115 °C and 170 - 185 °C.

Additional measurements with the capillary method were performed in order to clarify the results of the DSC measurements.

In the temperature range of 30 - 64 °C the test item appeared as unchanged white crystals. In the temperature range of 64 - 67 °C the test item changed into cloudy I waxy and partly melted (phase change of the liquid crystal). Above 109 - 111 °C the test item changed into a cloudy liquid (phase change of the liquid crystal). Above 179 °C the test item changed into a clear liquid (phase change of the liquid crystal, clearing point). Due to the results of the DSC measurements and the capillary measurements it is concluded that the test item has a melting range of 61 - 177 °C with the occurrence of at least one mesophase.

Description of key information

The test item has a melting range of 61 - 177 °C

Additional information

A study was conducted according to OECD TG 102 and Regulation (EC) No 440/2008 method A.1 to determine the melting point of the test item using differential scanning calorimetry and capillary tube method.

Two DSC-measurements in aluminium crucibles with a hole showed three endothermic effects in the temperature range of 60 - 75 °C, 105 - 115 °C and 170 - 185 °C.

Additional measurements with the capillary method were performed in order to clarify the results of the DSC measurements.

In the temperature range of 30 - 64 °C the test item appeared as unchanged white crystals. In the temperature range of 64 - 67 °C the test item changed into cloudy I waxy and partly melted (phase change of the liquid crystal). Above 109 - 111 °C the test item changed into a cloudy liquid (phase change of the liquid crystal). Above 179 °C the test item changed into a clear liquid (phase change of the liquid crystal, clearing point). Due to the results of the DSC measurements and the capillary measurements it is concluded that the test item has a melting range of 61 - 177 °C with the occurrence of at least one mesophase.