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Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

The 48-hour EC50 was estimated to be 0.108 mg Pt L-1.

Key value for chemical safety assessment

Additional information

A 48 -h acute immobilisation Daphnia magna study is available for diammonium hexachloroplatinate following OECD guideline 202 and EU Method C.2 (Simon 2014). A static test system was followed. Five test concentrations were used, and fresh and aged test solutions were analysed using ICP-OES. Due to recovery rates within a range of 80 – 120 % of nominal throughout the test, nominal test item concentrations were applied for effect assessment. All validity criteria were met. The 48-hour EC50 was estimated to be 0.284 mg test item L-1 (0.108 mg Pt L-1). The 48-hour NOEC was determined to be 0.200 mg test item L-1 (0.076 mg Pt L-1).


Comparison of the EC50 value from this study with the EC50 values for another platinum(IV) substance with a chloro ligand, hexachloroplatinic acid, indicate that the results are similar when expressed as platinum concentrations, with hexachloroplatinic acid being slightly more toxic. The EC50 value for diammonium hexachloroplatinate is 0.108 mg Pt L-1, whereas the EC50 values for hexachloroplatinic acid are 0.0205 mg Pt L-1 and 0.052 mg Pt L-1. These results indicate that for diammonium hexachloroplatinate the counter ion does not appear to increase the toxicity of the test item, and read across from hexachloroplatinic acid for other ecotoxicity endpoints is appropriate, and likely to be a worst case approach.