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EC number: 310-013-6 | CAS number: 102110-15-6 A complex combination of hydrocarbons obtained by distillation of the products from a steam-cracking process. It consists predominantly of hydrocarbons having carbon numbers of C5 and dicyclopentadiene and boiling in the range of approximately 30°C to 170°C (86°F to 338°F).
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Key value for chemical safety assessment
Genetic toxicity in vitro
Description of key information
In vitro and in vivo genotoxicity data are available for 2 streams within this category - CAS 68477-54-3 (Low Dicyclopentadiene Resin Oil) and CAS 68478-10-4 (Dicyclopentadiene/Codimer Concentrate). These studies show negative results. However, there are substantial data on the genotoxicity of some of the specific components present in some streams. Streams that contain ≥ 0.1% benzene are considered to be mutagenic and will require classification for this end-point.
Additional information
According to the testing proposal generated by the LOA REACH Consortium, all UVCB streams in Category L will tested for genetic toxicity endpoints. Full details are available in the testing proposal included in Section 13.
In vitro and in vivo genotoxicity data are available for two specific streams identified for this category:
CAS 68477-54-3 (Low Dicyclopentadiene Resin Oil): No positive mutagenic response was observed in a bacterial reverse mutation test using Salmonella typhimurium tester strains TA98, TA100, TA1535 and TA1537 and Escherichia coli tester strain WP2 uvrA in the presence and absence or Aroclor-induced rat liver S9 (ACC, 2004m). Negative results were also seen in vivo. Not statistically significant increase in micronucleated polychromatic erythrocytes was seen in male or female mouse bone marrow when evaluated after two administrations, approximately 24 hours apart. The highest dose administrated on the study was 1750 mg/Kg (ACC, 2004o).
CAS 68478-10-4 (Dicyclopentadiene/Codimer Concentrate): This stream was shown to have no mutagenic activity in a bacterial reverse mutation test using Salmonella typhimurium tester strains TA98, TA100, TA1535 and TA1537 and Escherichia coli tester strain WP2 uvrA in the presence and absence or Aroclor-induced rat liver S9 (ACC, 2004l). No evidence of genotoxicity was seen in an in vivo mouse micronucleus test dosed at 1750 mg/Kg (2 doses at 24 hour interval) (ACC, 2004n).
Specific components which have been identified as present in some streams and shown to be mutagenic in vivo:
Benzene (Classification: GHS/CLP - Category 1B, H340): Benzene has been extensively examined for mutagenicity both in vitro and in vivo in a range of recognised core assay types. It has shown mixed results for mutagenicity in vitro although in mammalian cells there is overall evidence for potential mutagenic activity (EU, 2008b). Benzene has been shown to be mutagenic in vivo in both somatic cells and germ cells (Ciranni et al, 1991).
References
EU (2008b). European Union Risk Assessment Report for Benzene. EC Joint Research Centre. http: //ecb. jrc. ec. europa. eu/documents/Existing-chemicals/RISK_ASSESSMENT/REPORT/benzenereport063. pdf.
Justification for classification or non-classification
Available data for streams in this category and specific components present within some streams indicate the Resin Oils and Cyclic Dienes that contain <0.1% benzene are considered not to be mutagenic and no classification will be required under Reg (EC) 1272/2008.
It is proposed that Resin Oils and Cyclic Dienes streams containing ≥0.1% benzene are classified as Cat 1B, H340 under Reg (EC) 1272/2008 “May cause genetic defects”. Resin Oils and Cyclic Dienes streams that contain <0.1% benzene.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

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