Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
March 10, 2008 to May 15, 2008
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008
Report Date:
2008

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
GLP compliance:
yes (incl. certificate)
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Specific details on test material used for the study:
TEST MATERIAL
Name ( stated on the report) : TETRAHYDRO CITRAL
Appearance: Colourless to pale yellow liquid
Batch: 7500118381
Expiry date: August 26, 2008

Study design

Analytical method:
high-performance liquid chromatography

Results and discussion

Partition coefficient
Key result
Type:
log Pow
Partition coefficient:
4.5
Temp.:
35 °C
pH:
7

Applicant's summary and conclusion

Conclusions:
The chromatograms show one peak with an average retention time of 10.93 minutes, corresponding to a partition coefficient (log value) of 4.5.
Therefore :Partition coefficient n-octanol/water of TETRAHYDROCITRAL: log Pow = 4.5
Executive summary:

The Partition Coefficient n-octanol/water of TETRAHYDROCITRAL was determined by the Reverse Phase High Performance Liquid Chromatographic Method according to the OECD Guidelines for Testing of Chemicals, Method No. 117.

 

The result is:

Partition coefficient n-octanol/water of TETRAHYDROCITRAL:log Pow= 4.5